Permanent disabilities following CNS injuries result from the failure of injured axons to
regenerate and rebuild functional connections with their original targets. By contrast, injury …

After an injury in the adult mammalian central nervous system (CNS), lesioned axons fail to
regenerate. This failure to regenerate contrasts with axons' remarkable potential to grow …

Primary somatosensory neurons are specialized to transmit specific types of sensory
information through differences in cell size, myelination, and the expression of distinct …

Summary N 6-methyladenosine (m 6 A) affects multiple aspects of mRNA metabolism and
regulates developmental transitions by promoting mRNA decay. Little is known about the …

Injured neurons in the adult mammalian central nervous system often die and seldom
regenerate axons. To uncover transcriptional pathways that could ameliorate these …

Enhancing the regeneration of axons is often considered to be a therapeutic target for
improving functional recovery after peripheral nerve injury. In this review, the evidence for …

Peripheral nerves injuries result in paralysis, anesthesia and lack of autonomic control of the
affected body areas. After injury, axons distal to the lesion are disconnected from the …

Axon regeneration in the mature mammalian central nervous system (CNS) is extremely
limited after injury. Consequently, functional deficits persist after spinal cord injury (SCI) …

The inability of neurons to regenerate long axons within the CNS is a major impediment to
improving outcome after spinal cord injury, stroke, and other CNS insults. Recent advances …

At least 30 types of retinal ganglion cells (RGCs) send distinct messages through the optic
nerve to the brain. Available strategies of promoting axon regeneration act on only some of …