The evolution of SARS-CoV-2

PV Markov, M Ghafari, M Beer, K Lythgoe… - Nature Reviews …, 2023 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused millions of
deaths and substantial morbidity worldwide. Intense scientific effort to understand the …

COVID-19: challenges of viral variants

JL Jacobs, G Haidar, JW Mellors - Annual Review of Medicine, 2023 - annualreviews.org
The COVID-19 pandemic has been accompanied by SARS-CoV-2 evolution and
emergence of viral variants that have far exceeded initial expectations. Five major variants of …

Tracking SARS-CoV-2 Omicron diverse spike gene mutations identifies multiple inter-variant recombination events

J Ou, W Lan, X Wu, T Zhao, B Duan, P Yang… - … and Targeted Therapy, 2022 - nature.com
The current pandemic of COVID-19 is fueled by more infectious emergent Omicron variants.
Ongoing concerns of emergent variants include possible recombinants, as genome …

SARS-CoV-2 prolonged infection during advanced HIV disease evolves extensive immune escape

S Cele, F Karim, G Lustig, JE San, T Hermanus… - Cell host & …, 2022 - cell.com
Characterizing SARS-CoV-2 evolution in specific geographies may help predict properties
of the variants that come from these regions. We mapped neutralization of a SARS-CoV-2 …

Cumulative SARS-CoV-2 mutations and corresponding changes in immunity in an immunocompromised patient indicate viral evolution within the host

ST Sonnleitner, M Prelog, S Sonnleitner… - Nature …, 2022 - nature.com
Different scenarios explaining the emergence of novel variants of concern (VOC) of the
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been reported …

SARS-CoV-2 viral clearance and evolution varies by type and severity of immunodeficiency

Y Li, MC Choudhary, J Regan, J Boucau… - Science translational …, 2024 - science.org
Despite vaccination and antiviral therapies, immunocompromised individuals are at risk for
prolonged severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, but the …

The origins and molecular evolution of SARS-CoV-2 lineage B. 1.1. 7 in the UK

V Hill, L Du Plessis, TP Peacock, D Aggarwal… - Virus …, 2022 - academic.oup.com
The first SARS-CoV-2 variant of concern (VOC) to be designated was lineage B. 1.1. 7, later
labelled by the World Health Organization as Alpha. Originating in early autumn but …

Accelerated SARS-CoV-2 intrahost evolution leading to distinct genotypes during chronic infection

C Chaguza, AM Hahn, ME Petrone, S Zhou… - Cell Reports …, 2023 - cell.com
The chronic infection hypothesis for novel severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) variant emergence is increasingly gaining credence following the …

Want to prevent pandemics? Stop spillovers

NM Vora, L Hannah, S Lieberman, MM Vale… - Nature, 2022 - nature.com
Want to prevent pandemics? Stop spillovers Skip to main content Thank you for visiting
nature.com. You are using a browser version with limited support for CSS. To obtain the best …

Recurrent SARS-CoV-2 mutations in immunodeficient patients

SAJ Wilkinson, A Richter, A Casey, H Osman… - Virus …, 2022 - academic.oup.com
Long-term severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in
immunodeficient patients are an important source of variation for the virus but are …