'Toxic Masculinity': What Is Known about the Role of Androgen Receptors in Head and Neck Squamous Cell Carcinoma

J Čonkaš, M Sabol, P Ozretić - International journal of molecular sciences, 2023 - mdpi.com
Head and neck squamous cell carcinoma (HNSCC), the most prevalent cancer in the head
and neck region, develops from the mucosal epithelium of the upper aerodigestive tract. Its …

Let's Talk about Sex Hormone Receptors and Their Physical Interaction with Sonic Hedgehog Protein: A Computational Study with Emphasis on Progesterone …

A Tomić, J Čonkaš, P Ozretić - Applied Sciences, 2024 - mdpi.com
Featured Application Targeting interaction between sonic hedgehog protein and sex
hormone receptors might be a valuable strategy for the treatment of endocrine-resistant …

[HTML][HTML] Mortalin promotes the evolution of androgen-independent prostate cancer through Wnt/β-catenin signaling pathway

Y Chang, J Sui, Q Fu, Z Lu, Z Piao, T Jin… - Cancer Cell …, 2024 - ncbi.nlm.nih.gov
Prostate cancer (PC) is a major global health concern affecting male individuals. Among its
variants, androgen-independent prostate cancer exhibits slow progression and lacks …

How does Hedgehog signaling participate in the cross-interaction of hormones and testis development?

JUNJIE YU, WANXI YANG - Biocell, 2025 - Elsevier
Hedgehog (HH) signaling has been researched for decades and Hedgehog has 3
homologs: Sonic Hedgehog (Shh), Indian Hedgehog (Ihh), and Desert Hedgehog (Dhh) …

GLI transcriptional targets S100A7 and KRT16 show upregulated expression patterns in epidermis overlying the tumor mass in melanoma samples

M Kurtović, N Piteša, J Čonkaš, H Hajpek… - International journal of …, 2024 - mdpi.com
Although not completely understood, the role of the Hedgehog-GLI (HH-GLI) signaling
pathway in melanoma and epithelial skin tumors has been reported before. In this study, we …

Higher expressions of SHH and AR are associated with a positive receptor status and have impact on survival in a cohort of croatian breast cancer patients

I Budimir, Č Tomasović-Lončarić, K Kralik, J Čonkaš… - Life, 2022 - mdpi.com
Breast cancers (BC) are usually classified into four molecular subtypes according to the
expression of estrogen (ER), progesterone (PR), and human epidermal growth factor 2 …

Ekspresija proteina GLI1 i S100A7 u melanomu čovjeka

H Hajpek - 2024 - repozitorij.pmf.unizg.hr
Sažetak Signalni put Hedgehog važan je tijekom embrionalnog razvoja, te u odraslom
organizmu u održavanju homeostaze tkiva. Otkriće aberantne aktivacije puta Hedgehog kod …

Interakcija proteina sonic hedgehog s receptorima estrogena i androgena u karcinomima dojke

I Budimir - 2022 - repozitorij.unios.hr
Sažetak Cilj istraživanja: Aktivnost HH-GLI signalnog kao i receptora androgena opisana je
u karcinomu dojke, no i dalje bez jasnog mehanizma djelovanja pa tako i jasne uloge. U …