There is evidence from high quality studies to strongly support the positive association
between increased levels of physical activity, exercise participation and improved health in …

From a biological point of view, aging can be considered a progressive inability of an
organism to react to stress, maintain homeostasis, and survive unfavourable changes during …

'How Emotions Are Made did what all great books do. It took a subject I thought I understood
and turned my understanding upside down'–Malcolm Gladwell, author of The Tipping Point …

OBJECTIVE: In mouse, PGC1-α overexpression in muscle stimulates an increase in
expression of FNDC5, a membrane protein that is cleaved and secreted as a newly …

Irisin was recently identified as a putative myokine that is induced by exercise. Studies
suggest that it is produced by cleavage of the FNDC5 (fibronectin domain-containing protein …

Aims/hypothesis Biomarkers of endothelial dysfunction and low-grade inflammation are
important in the pathogenesis of CVD and can potentially be modified by physical activity …

The erythrocyte sedimentation rate (ESR) is a routine test for inflammation. Few studies have
investigated the potential influence of lifestyle factors and common metabolic abnormalities …

Abstract Aims/Hypothesis Irisin is a novel, myocyte secreted, hormone that has been
proposed to mediate the beneficial effects of exercise on metabolism. Irisin is expressed, at …

Our primary aim was to study the effects of 24 weeks of combined aerobic and resistance
training performed on the same day or on different days on inflammation markers. Physically …

Since the 19th century, many studies have enlightened the role of inflammation in
atherosclerosis, changing our perception of “vessel plaque due to oxidized lipoproteins” …