[HTML][HTML] Emerging trends and innovations in the treatment and diagnosis of atherosclerosis and cardiovascular disease: a comprehensive review towards healthier …

I Alradwan, N Al Fayez, MN Alomary, AA Alshehri… - Pharmaceutics, 2024 - mdpi.com
Cardiovascular diseases (CVDs) are classed as diseases of aging, which are associated
with an increased prevalence of atherosclerotic lesion formation caused by such diseases …

Emerging technologies for cardiac tissue engineering and artificial hearts

L Sun, Y Wang, D Xu, Y Zhao - Smart Medicine, 2023 - Wiley Online Library
Heart diseases, especially cardiovascular diseases, have brought heavy burden on society
for their high morbidity and mortality. In clinical, heart transplantation is recognized as an …

[HTML][HTML] Advanced heart failure: state of the art and future directions

D Masarone, M Kittleson, A Petraio… - Reviews in …, 2022 - imrpress.com
Advanced heart failure is a clinical challenge that requires a pathophysiological-based
approach. As the field has been the subject of multiple reviews, the objective of this paper is …

Exoskeleton Partial‐Coated Stem Cells for Infarcted Myocardium Restoring

H He, Y Yuan, Y Wu, J Lu, X Yang, K Lu… - Advanced …, 2023 - Wiley Online Library
The integration of abiotic materials with live cells has emerged as an exciting strategy for the
control of cellular functions. Exoskeletons consisting ofmetal–organic frameworks are …

Fibrin, bone marrow cells and macrophages interactively modulate cardiomyoblast fate

I Borrego, A Frobert, G Ajalbert, J Valentin… - Biomedicines, 2022 - mdpi.com
Interactions between macrophages, cardiac cells and the extracellular matrix are crucial for
cardiac repair following myocardial infarction (MI). We hypothesized that cell-based …

Mass customized outlook for regenerative heart failure care

S Yamada, J Bartunek, A Behfar, A Terzic - International journal of …, 2021 - mdpi.com
Heart failure pathobiology is permissive to reparative intent. Regenerative therapies
exemplify an emerging disruptive innovation aimed at achieving structural and functional …

Stem cell-derived extracellular vesicles in the treatment of cardiovascular diseases

J McDonald, S Mohak, Z Fabian - Pharmaceutics, 2024 - mdpi.com
Cardiovascular disease constitutes a noteworthy public health challenge characterized by a
pronounced incidence, frequency, and mortality rate, particularly impacting specific …

The Long and Winding Road to Cardiac Regeneration

AM Sacco, C Castaldo, F Di Meglio, D Nurzynska… - Applied Sciences, 2023 - mdpi.com
Cardiac regeneration is a critical endeavor in the treatment of heart diseases, aimed at
repairing and enhancing the structure and function of damaged myocardium. This review …

IL-6 coaxes cellular dedifferentiation as a pro-regenerative intermediate that contributes to pericardial ADSC-induced cardiac repair

H Zhu, X Liu, Y Ding, K Tan, W Ni, W Ouyang… - Stem Cell Research & …, 2022 - Springer
Background Cellular dedifferentiation is a regenerative prerequisite that warrants cell cycle
reentry and appropriate mitotic division during de novo formation of cardiomyocytes. In the …

Mechanisms of cardiac repair in cell therapy

BC Collet, DR Davis - Heart, Lung and Circulation, 2023 - Elsevier
Heart failure is an important cause of morbidity and mortality. More than 20 years ago,
special interest was drawn to cell therapy as a means of restoring damaged hearts to …