Dengue vaccine: an update

CH Huang, YT Tsai, SF Wang, WH Wang… - Expert Review of Anti …, 2021 - Taylor & Francis
Introduction: Dengue virus is a global health threat, with approximately 390 million dengue
infections annually. Efficient vaccines for dengue prevention are currently lacking. This …

Recent developments in recombinant protein–based dengue vaccines

NK Tripathi, A Shrivastava - Frontiers in immunology, 2018 - frontiersin.org
Recombinant proteins are gaining enormous importance these days due to their wide
application as biopharmaceutical products and proven safety record. Various recombinant …

Structure and function of capsid protein in flavivirus infection and its applications in the development of vaccines and therapeutics

X Zhang, Y Zhang, R Jia, M Wang, Z Yin, A Cheng - Veterinary research, 2021 - Springer
Flaviviruses are enveloped single positive-stranded RNA viruses. The capsid (C), a
structural protein of flavivirus, is dimeric and alpha-helical, with several special structural …

Dengue viruses and promising envelope protein domain III-based vaccines

H Fahimi, M Mohammadipour… - Applied microbiology …, 2018 - Springer
Dengue viruses are emerging mosquito-borne pathogens belonging to Flaviviridae family
which are transmitted to humans via the bites of infected mosquitoes Aedes aegypti and …

[HTML][HTML] Targets and strategies for vaccine development against dengue viruses

WH Wang, AN Urbina, CY Lin, ZS Yang… - Biomedicine & …, 2021 - Elsevier
Dengue virus (DENV) is a global health threat causing about half of the worldwide
population to be at risk of infection, especially the people living in tropical and subtropical …

Synthesis, LC-MS/MS analysis, and biological evaluation of two vaccine candidates against ticks based on the antigenic P0 peptide from R. sanguineus linked to the p64K …

LJ González, PE Encinosa Guzmán… - Analytical and …, 2021 - Springer
A peptide from the P0 acidic ribosomal protein (pP0) of ticks conjugated to keyhole limpet
hemocyanin from Megathura crenulata has shown to be effective against different tick …

[HTML][HTML] Next generation dengue vaccines: a review of the preclinical development pipeline

KS Vannice, JT Roehrig, J Hombach - Vaccine, 2015 - Elsevier
Dengue represents a significant and growing public health problem across the globe, with
approximately half of the world's population at risk. The increasing and expanding burden of …

A novel tetravalent formulation combining the four aggregated domain III-capsid proteins from dengue viruses induces a functional immune response in mice and …

E Suzarte, L Gil, I Valdés, E Marcos… - International …, 2015 - academic.oup.com
Our group developed a subunit vaccine candidate against dengue virus based on two
different viral regions: the domain III of the envelope protein and the capsid protein. The …

Development of MVA-d34 Tetravalent Dengue Vaccine: Design and Immunogenicity

RR Mintaev, DV Glazkova, OV Orlova, GM Ignatyev… - Vaccines, 2023 - mdpi.com
Dengue fever, an infectious disease that affects more than 100 million people every year, is
a global health problem. Vaccination may be the most effective prevention strategy for the …

[HTML][HTML] Designing of a multiepitope-based chimeric vaccine against dengue virus serotype 3 (DENV-3) through next generation reverse vaccinology approaches

MHU Masum, J Ferdous, S Lokman… - Informatics in Medicine …, 2024 - Elsevier
The dengue virus (DENV) causes dengue infection and has become a significant global
public health concern. The successful application of immunotherapies in treating dengue …