[HTML][HTML] Overcoming Cancer Multi-drug Resistance (MDR): Reasons, mechanisms, nanotherapeutic solutions, and challenges

C Duan, M Yu, J Xu, BY Li, Y Zhao… - Biomedicine & …, 2023 - Elsevier
Multi-drug resistance (MDR) in cancer cells, either intrinsic or acquired through various
mechanisms, significantly hinders the therapeutic efficacy of drugs. Typically, the reduced …

High-intensity focused ultrasound: a review of mechanisms and clinical applications

VS Bachu, J Kedda, I Suk, JJ Green, B Tyler - Annals of biomedical …, 2021 - Springer
Abstract High Intensity Focused Ultrasound (HIFU) is an emerging and increasingly useful
modality in the treatment of cancer and other diseases. Although traditional use of …

Advances in nanomaterial-based targeted drug delivery systems

X Cheng, Q Xie, Y Sun - Frontiers in bioengineering and …, 2023 - frontiersin.org
Nanomaterial-based drug delivery systems (NBDDS) are widely used to improve the safety
and therapeutic efficacy of encapsulated drugs due to their unique physicochemical and …

[HTML][HTML] Micro/nano-bubble-assisted ultrasound to enhance the EPR effect and potential theranostic applications

L Duan, L Yang, J Jin, F Yang, D Liu, K Hu, Q Wang… - Theranostics, 2020 - ncbi.nlm.nih.gov
Drug delivery for tumor theranostics involves the extensive use of the enhanced permeability
and retention (EPR) effect. Previously, various types of nanomedicines have been …

Cytotoxicity of metal‐based nanoparticles: from mechanisms and methods of evaluation to pathological manifestations

P Xiong, X Huang, N Ye, Q Lu, G Zhang… - Advanced …, 2022 - Wiley Online Library
Metal‐based nanoparticles (NPs) are particularly important tools in tissue engineering‐,
drug carrier‐, interventional therapy‐, and biobased technologies. However, their complex …

[HTML][HTML] Multifunctional nanostructures: Intelligent design to overcome biological barriers

M Azizi, R Jahanban-Esfahlan, H Samadian… - Materials Today Bio, 2023 - Elsevier
Over the past three decades, nanoscience has offered a unique solution for reducing the
systemic toxicity of chemotherapy drugs and for increasing drug therapeutic efficiency …

Fluorescence thermometers: intermediation of fundamental temperature and light

G Feng, H Zhang, X Zhu, J Zhang, J Fang - Biomaterials Science, 2022 - pubs.rsc.org
The rapid advancement of thermal materials and fluorescence spectroscopy has extensively
promoted the development of micro-scale fluorescence thermometry in recent years. Based …

Smart Nanosystems for Overcoming Multiple Biological Barriers in Cancer Nanomedicines Transport: Design Principles, Progress, and Challenges

G Lin, J Zhou, H Cheng, G Liu - Small, 2023 - Wiley Online Library
The development of smart nanosystems, which could overcome diverse biological barriers
of nanomedicine transport, has received intense scientific interest in improving the …

US/PA/MR multimodal imaging-guided multifunctional genetically engineered bio-targeted synergistic agent for tumor therapy

L Ren, Y Wang, Y Tang, F Wang, Y Du, X Ou… - Journal of …, 2024 - Springer
Focused ultrasound ablation surgery (FUAS) is a minimally invasive treatment option that
has been utilized in various tumors. However, its clinical advancement has been hindered …

Dual‐Cascade Activatable Nanopotentiators Reshaping Adenosine Metabolism for Sono‐Chemodynamic‐Immunotherapy of Deep Tumors

M Zhan, F Wang, Y Liu, J Zhou, W Zhao, L Lu… - Advanced …, 2023 - Wiley Online Library
Immunotherapy is an attractive treatment strategy for cancer, while its efficiency and safety
need to be improved. A dual‐cascade activatable nanopotentiator for sonodynamic therapy …