Liquid chromatography (LC) coupled to mass spectrometry (MS) or tandem mass
spectrometry (MS/MS) is a well-established and widely used technique in clinical and …

Fixed-dose combinations (FDCs) refer to products containing two or more active ingredients
combined in a single dosage form. The FDCs are justified because of several advantages …

Abstract LC–high resolution (HR)-MS well established in proteomics has become more and
more important in bioanalysis of small molecules over the last few years. Its high selectivity …

Orbitrap technology was successfully applied for broad metabolite-based LC-high resolution
(HR)-MS screening of drugs in clinical and forensic toxicology. This paper aims to elucidate …

Postmortem drug redistribution (PMR) is a well-known phenomenon in forensic toxicology
with implications for medico-legal death investigations. Paired antemortem (AM) specimen …

A broad drug screening method for toxicologically significant drugs and metabolites in whole
blood using liquid chromatography time-of-flight mass spectrometry (LC/QTOF) was …

The described procedure provides a rapid technique for the detection and semi-quantitation
of a large number of drugs in blood. This procedure uses a minimal sample volume and …

The aim of the study was to develop a LC–MS-MS method able to detect and quantify a
number of frequently prescribed antipsychotic and antidepressant drugs for toxicological …

Driving under the influence of drug (DUID) cases continue to challenge forensic toxicologists
as both the volume and complexity of casework increases. Comprehensive DUID testing …

Nimodipine (NMD) has gained increasing attention in the latest scientific studies as it can act
alone or in combination with other drugs to relieve or prevent symptoms of traumatic brain …