Intracellular delivery is a key step in biological research and has enabled decades of
biomedical discoveries. It is also becoming increasingly important in industrial and medical …

Intracellular delivery of materials has become a critical component of genome-editing
approaches, ex vivo cell-based therapies, and a diversity of fundamental research …

The discovery of somatic cell nuclear transfer proved that somatic cells can carry the same
genetic code as the zygote, and that activating parts of this code are sufficient to reprogram …

Synthetic mRNA has emerged as a powerful tool for the transfer of genetic information, and it
is being explored for a variety of therapeutic applications. Many of these applications require …

Introduction: Our previous scientometric review of regenerative medicine provides a
snapshot of the fast-growing field up to the end of 2011. The new review identifies emerging …

A large number of clinical trials have shown stem cell therapy to be a promising therapeutic
approach for the treatment of cardiovascular diseases. Since the first transplantation into …

With the advent of next generation sequencing techniques a previously unknown world of
non-coding RNA molecules have been discovered. Non-coding RNA transcripts likely …

The ectopic expression of transcription factors can reprogram cell fate, yet it is unknown how
the initial binding of factors to the genome relates functionally to the binding seen in the …

The field of stem-cell biology has been catapulted forward by the startling development of
reprogramming technology. The ability to restore pluripotency to somatic cells through the …

Regenerative medicine aims to replace the lost or damaged cells in the human body
through a new source of healthy transplanted cells or by endogenous repair. Although …