5-Fluorouracil: a narrative review on the role of regulatory mechanisms in driving resistance to this chemotherapeutic agent

S Ghafouri-Fard, A Abak, F Tondro Anamag… - Frontiers in …, 2021 - frontiersin.org
5-fluorouracil (5-FU) is among the mostly administrated chemotherapeutic agents for a wide
variety of neoplasms. Non-coding RNAs have a central impact on the determination of the …

Current insights into the metastasis of epithelial ovarian cancer-hopes and hurdles

M Yousefi, S Dehghani, R Nosrati, M Ghanei… - Cellular Oncology, 2020 - Springer
Background Ovarian cancer is the most lethal gynecologic cancer and the fifth leading
cause of cancer-related mortality in women worldwide. Despite various attempts to improve …

Pharmacogenomics of 5-fluorouracil in colorectal cancer: review and update

P Xie, JL Mo, JH Liu, X Li, LM Tan, W Zhang, HH Zhou… - Cellular oncology, 2020 - Springer
Background Colorectal cancer (CRC) is a disease with high morbidity and mortality rates. 5-
fluorouracil (5-FU) is the first-line recommended drug for chemotherapy in patients with …

A near-infrared photoelectrochemical aptasensing system based on Bi2O2S nanoflowers and gold nanoparticles for high-performance determination of MCF-7 cells

X Xu, Z Ding, X Zhang, R Zha, W Li, L Xu, D Sun… - Analytica Chimica …, 2023 - Elsevier
Circulating tumor cells (CTCs) are commonly considered as the major cause of tumor
metastasis and can eventually lead to death. Therefore, developing a high-performance …

Preclinical models to study patient-derived circulating tumor cells and metastasis

KN Suvilesh, Y Manjunath, K Pantel, JT Kaifi - Trends in Cancer, 2023 - cell.com
Circulating tumor cells (CTCs) that are detached from the tumor can be precursors of
metastasis. The majority of studies focus on enumeration of CTCs from patient blood to …

miRNA-148b and its role in various cancers

N Dorraki, ZN Ghale-Noie, NS Ahmadi, V Keyvani… - …, 2021 - Taylor & Francis
miRNA-148b belongs to the family miR-148/-152, with significant differences in nonseed
sequences, which can target diverse mRNA molecules. Reportedly, it may undergo …

Circulating tumor cells in colorectal cancer in the era of precision medicine

M Hu, Z Wang, Z Wu, P Ding, R Pei, Q Wang… - Journal of Molecular …, 2022 - Springer
Colorectal cancer (CRC) is one of the main causes of cancer-related morbidity and mortality
across the globe. Although serum biomarkers such as carcinoembryonic antigen (CEA) and …

[HTML][HTML] Liquid biopsy leads to a paradigm shift in the treatment of pancreatic cancer

F Watanabe, K Suzuki, H Noda… - World Journal of …, 2022 - ncbi.nlm.nih.gov
Pancreatic ductal adenocarcinoma (PDAC) is one of the most cancers. Its 5-year survival
rate is very low. The recent induction of neoadjuvant chemotherapy and improvements in …

Circulating tumor cells dynamics during chemotherapy predict survival and response in advanced non-small-cell lung cancer patients

Z Wang, XC Zhang, WN Feng, L Zhang… - Therapeutic …, 2023 - journals.sagepub.com
Background: Circulating tumor cells (CTCs) are prognostic biomarker in non-small-cell lung
cancer (NSCLC). CTCs could also be used as predictor of efficacy of systemic treatments in …

Decoding lung cancer at single-cell level

XX Fan, Q Wu - Frontiers in Immunology, 2022 - frontiersin.org
Lung cancer is the leading cause of cancer death due to its high degree of malignancy,
rapid growth, and early metastasis. Recent studies have found that lung cancer has a high …