Accumulating evidence shows that oxidative stress plays an essential role in the
pathogenesis and progression of many diseases. The imbalance between the production of …

The pathobiology of atherosclerotic disease requires further elucidation to discover new
approaches to address its high morbidity and mortality. To date, over 17 million …

Aortic aneurysm, including thoracic aortic aneurysm and abdominal aortic aneurysm, is the
second most prevalent aortic disease following atherosclerosis, representing the ninth …

Aortic aneurysm is a chronic aortic disease affected by many factors. Although it is generally
asymptomatic, it poses a significant threat to human life due to a high risk of rupture …

Insulin resistance (IR), defined as an attenuated biological response to circulating insulin, is
a fundamental defect in obesity and type 2 diabetes (T2D), and is also linked to a wide …

National space agencies and private corporations aim at an extended presence of humans
in space in the medium to long term. Together with currently suboptimal technology …

Arterial occlusive disease is the leading cause of death in Western countries. Core
contemporary therapies for this disease include angioplasties, stents, endarterectomies and …

Despite the great advances that the tissue engineering field has experienced over the last
two decades, the amount of in vitro engineered tissues that have reached a stage of clinical …

On Earth, humans are subjected to a gravitational force that has been an important
determinant in human evolution and function. During spaceflight, astronauts are subjected to …

Increasing evidence has associated the exposure of endocrine-disrupting chemicals (EDCs)
with the cardiovascular (CV) system. This exposure is particularly problematic in a sensitive …