Force spectroscopy of single cells using atomic force microscopy

A Viljoen, M Mathelié-Guinlet, A Ray… - Nature Reviews …, 2021 - nature.com
Physical forces and mechanical properties have critical roles in cellular function, physiology
and disease. Over the past decade, atomic force microscopy (AFM) techniques have …

Mechanomicrobiology: how bacteria sense and respond to forces

YF Dufrêne, A Persat - Nature Reviews Microbiology, 2020 - nature.com
Microorganisms have evolved to thrive in virtually any terrestrial and marine environment,
exposing them to various mechanical cues mainly generated by fluid flow and pressure as …

Micro-and nanotopography sensitive bacterial attachment mechanisms: a review

Y Cheng, G Feng, CI Moraru - Frontiers in microbiology, 2019 - frontiersin.org
Bacterial attachment to material surfaces can lead to the development of biofilms that cause
severe economic and health problems. The outcome of bacterial attachment is determined …

Adaptable hydrogel networks with reversible linkages for tissue engineering

H Wang, SC Heilshorn - Advanced Materials, 2015 - Wiley Online Library
Adaptable hydrogels have recently emerged as a promising platform for three‐dimensional
(3D) cell encapsulation and culture. In conventional, covalently crosslinked hydrogels …

Mechanical forces in the immune system

M Huse - Nature Reviews Immunology, 2017 - nature.com
Leukocytes can completely reorganize their cytoskeletal architecture within minutes. This
structural plasticity, which facilitates their migration and communicative function, also …

The mechanical world of bacteria

A Persat, CD Nadell, MK Kim, F Ingremeau… - Cell, 2015 - cell.com
In the wild, bacteria are predominantly associated with surfaces as opposed to existing as
free-swimming, isolated organisms. They are thus subject to surface-specific mechanics …

The minimal cadherin-catenin complex binds to actin filaments under force

CD Buckley, J Tan, KL Anderson, D Hanein… - Science, 2014 - science.org
INTRODUCTION Cadherins are an ancient class of transmembrane proteins that are
essential for the formation of multicellular tissues in metazoans. Cadherins link intercellular …

Dynamic molecular processes mediate cellular mechanotransduction

BD Hoffman, C Grashoff, MA Schwartz - Nature, 2011 - nature.com
Cellular responses to mechanical forces are crucial in embryonic development and adult
physiology, and are involved in numerous diseases, including atherosclerosis …

Multiparametric imaging of biological systems by force-distance curve–based AFM

YF Dufrêne, D Martínez-Martín, I Medalsy, D Alsteens… - Nature …, 2013 - nature.com
A current challenge in the life sciences is to understand how biological systems change their
structural, biophysical and chemical properties to adjust functionality. Addressing this issue …

Bacterial transport suppressed by fluid shear

R Rusconi, JS Guasto, R Stocker - Nature physics, 2014 - nature.com
Bacteria often live in dynamic fluid environments,, and flow can affect fundamental microbial
processes such as nutrient uptake, and infection. However, little is known about the …