Application of Biomaterials in the Development of Hydrogel-Forming Microneedles Integrated with a Cyclodextrin Drug Reservoir for Improved Pharmacokinetic …

CK Enggi, S Sulistiawati, A Himawan… - ACS Biomaterials …, 2024 - ACS Publications
Telmisartan (TEL) is a promising antihypertensive agent among other angiotensin receptor
blockers. However, its oral application is limited by its poor water solubility. This study …

A prediction model based on artificial intelligence techniques for disintegration time and hardness of fast disintegrating tablets in pre-formulation tests

M Momeni, M Afkanpour, S Rakhshani… - BMC Medical Informatics …, 2024 - Springer
Background The pharmaceutical industry is continually striving to innovate drug
development and formulation processes. Orally disintegrating tablets (ODTs) have gained …

Fast dissolving drug delivery systems: formulation, preparation techniques and evaluation

S Singh, T Virmani, R Virmani, G Mahlawat… - Universal Journal of …, 2018 - ujpronline.com
Abstract The Fast Dissolving Drug Delivery Systems sets a new benchmark was an
expansion that came into existence in the early 1980's and combat over the use of the …

Application of dual modified corn starch as a polymer for the colon targeted direct compressible budesonide tablet

A Gangopadhyay, A Bose, SS Rout… - Journal of Drug Delivery …, 2022 - Elsevier
In the current study, dually modified retrograded acetylated corn starch was prepared with
improved physicochemical properties than its native form. The modified starch was utilized …

Fast disintegrating tablet of Valsartan for the treatment of pediatric hypertension: In vitro and in vivo evaluation

RA Husseiny, ASA Lila, MH Abdallah… - Journal of Drug Delivery …, 2018 - Elsevier
Fast disintegrating tablets (FDTs) dissolve or disintegrate in the mouth without the need of
additional water. The aim of the present study was to formulate FDTs of Valsartan for the …

Formulation of olanzapine nanosuspension based orally disintegrating tablets (ODT); comparative evaluation of lyophilization and electrospraying process as …

N Anup, S Thakkar, M Misra - Advanced Powder Technology, 2018 - Elsevier
Olanzapine (OLAN) as an antipsychotic agent has shown its potential in effective
management of psychotic disorders however its use is limited because of its poor water …

Recent strategic developments in the use of superdisintegrants for drug delivery

PHL Tran, TTD Tran - Current pharmaceutical design, 2020 - ingentaconnect.com
Improving drug bioavailability in the pharmaceutical field is a challenge that has attracted
substantial interest worldwide. The controlled release of a drug can be achieved with a …

Formulation development and evaluation of fast disintegrating tablets of salbutamol sulphate, cetirizine hydrochloride in combined pharmaceutical dosage form: a new …

D Sharma, G Singh, D Kumar… - Journal of drug delivery, 2015 - Wiley Online Library
The objective of the present study was to prepare the fast disintegrating tablet of Salbutamol
Sulphate, Cetirizine Hydrochloride in combined tablet dosage form for respiratory disorders …

Rheological behavior and release dynamics of pregelatinized pink potato starch modified by stearic acid.

R Kumar, JF Kennedy, KJ Kumar - International Journal of Biological …, 2024 - Elsevier
The effects of stearic acid (5%, 10%, and 15% w/w) and pregelatinized pink potato starch
(20, 25, and 30 min) on complex formation, physicochemical properties, rheology, and …

Effect of annealing time on the applicability of potato starch as an excipient for the fast disintegrating propranolol hydrochloride tablet

A Gangopadhyay, R Saha, A Bose, RN Sahoo… - Journal of Drug Delivery …, 2022 - Elsevier
Starch is a cheap and easily available excipient in pharmaceutical manufacturing. Although
tablet formulated containing native starch have rapid disintegrating property, these products …