The advent of genome editing has transformed the therapeutic landscape for several
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …

Drug delivery systems for cancer chemotherapy are employed to improve the effectiveness
and decrease the side-effects of highly toxic drugs. Most chemotherapy agents have …

The interaction of Rebeccamycin with calf thymus (ctDNA) in the absence and presence of
H1 was investigated by molecular dynamics, multi-spectroscopic, and cellular techniques …

With advances in new drug therapies, it is essential to understand the interactions between
drugs and target molecules. In this study, we applied multiple spectroscopic techniques …

Berberine (BH) is an important traditional medicinal herb endowed with diverse
pharmacological and biological activities. In this work, the binding characteristics and …

DNA is an anisotropic, water-attracting, and biocompatible material, an ideal building block
for hydrogel. The alignment of the anisotropic DNA chains is essential to maximize hydrogel …

This review is aimed to provide extensive survey of quinolones and fluoroquinolones for a
variety of applications ranging from metal complexes and nanoparticle development to …

Background The infrared (IR) analysis of dried samples of DNA and DNA-polypeptide
complexes is still scarce. Here we have studied the FT-IR profiles of these components to …

Due to the potential use as transfecting agents of nucleic acids (DNA or RNA), multivalent
cationic non-viral vectors have received special attention in the last decade. Much effort has …

Mitochondrial DNA (mtDNA) plays a crucial but incompletely understood role in cellular
biochemistry and etiology of numerous disease states. Thus, there is an urgent need for …