Ghrelin is an octanoylated peptide acting by the activation of the growth hormone
secretagogue receptor, namely, GHS-R1a. The involvement of ghrelin in several …

Ghrelin is a peptide that is produced by endocrine cells that are primarily localized in the
stomach. Ghrelin receptors (GHSR) are expressed in the brain and periphery. Preclinical …

Drug addiction causes constant serious health, social, and economic burden within the
human society. The current drug dependence pharmacotherapies, particularly relapse …

Background Childhood adversity is a major risk factor for cardiometabolic health problems.
Stress-related changes in diet suggest a role for endocrine factors that influence dietary …

BACKGROUND Studies have demonstrated the role of ghrelin in alcohol-related behaviors
and consumption. Blockade of the growth hormone secretagogue receptor (GHSR), which is …

Despite increased awareness of aldehyde oxidase (AO) as a major drug-metabolising
enzyme, predicting the pharmacokinetics of its substrates remains challenging. Several drug …

Ghrelin modulates several biological functions via selective activation of the growth
hormone secretagogue receptor (GHSR). GHSR agonists may be useful for the treatment of …

Aims Currently, the only effective treatment for morbid obesity and its comorbidities is weight
loss surgery (WLS). Growing evidence suggests that different types of WLS, such as Roux …

In the present study, we investigated the effects of the glucagon-like peptide-1 (GLP-1)
agonist exendin-4 (Ex-4) on the stimulatory action of neuropeptide Y (NPY) and ghrelin …

Background: Rates of risky drinking are continuing to rise, particularly in women, yet sex as
a biological variable has been largely ignored. An emerging yet understudied potential …