Recent advances in bioprobes and biolabels based on cyanine dyes

X Ma, L Shi, B Zhang, L Liu, Y Fu, X Zhang - Analytical and bioanalytical …, 2022 - Springer
As a functional dye, cyanine dye promotes the widespread application of bioprobes in the
fields of medicine, genetics and environment, owing to its advantages of good photophysical …

Recent developments in G-quadruplex probes

DL Ma, Z Zhang, M Wang, L Lu, HJ Zhong… - Chemistry & Biology, 2015 - cell.com
Accumulating evidence has linked G-quadruplex structures to a number of biological
processes in vivo, including DNA replication, transcription, and genomic maintenance …

Thioflavin T as an efficient inducer and selective fluorescent sensor for the human telomeric G-quadruplex DNA

J Mohanty, N Barooah, V Dhamodharan… - Journal of the …, 2013 - ACS Publications
The quest for a G-quadruplex specific fluorescent sensor among other DNA forms under
physiological salt conditions has been addressed in this article. We demonstrate for the first …

Thioflavin T as an efficient fluorescence sensor for selective recognition of RNA G-quadruplexes

S Xu, Q Li, J Xiang, Q Yang, H Sun, A Guan, L Wang… - Scientific Reports, 2016 - nature.com
Abstract RNA G-quadruplexes (G4s) play important roles in translational regulation, mRNA
processing events and gene expression. Therefore, a fluorescent probe that is capable of …

Rational design of small-molecules to recognize G-quadruplexes of c-MYC promoter and telomere and the evaluation of their in vivo antitumor activity against breast …

W Long, BX Zheng, Y Li, XH Huang, DM Lin… - Nucleic acids …, 2022 - academic.oup.com
DNA G4-structures from human c-MYC promoter and telomere are considered as important
drug targets; however, the developing of small-molecule-based fluorescent binding ligands …

Design of Modular G‐quadruplex Ligands

AR Duarte, E Cadoni, AS Ressurreição… - …, 2018 - Wiley Online Library
Guanine‐rich nucleic acid sequences able to form four‐stranded structures (G‐
quadruplexes, G4) play key cellular regulatory roles and are considered as promising drug …

Beyond small molecules: targeting G-quadruplex structures with oligonucleotides and their analogues

E Cadoni, L De Paepe, A Manicardi… - Nucleic Acids …, 2021 - academic.oup.com
Abstract G-Quadruplexes (G4s) are widely studied secondary DNA/RNA structures, naturally
occurring when G-rich sequences are present. The strategic localization of G4s in genome …

Green and red fluorescent dyes for translational applications in imaging and sensing analytes: A dual‐color flag

E Oliveira, E Bértolo, C Núñez, V Pilla… - …, 2018 - Wiley Online Library
Red and green are two of the most‐preferred colors from the entire chromatic spectrum, and
red and green dyes are widely used in biochemistry, immunohistochemistry, immune …

Chemistry of Ketene N,S-Acetals: An Overview

L Zhang, J Dong, X Xu, Q Liu - Chemical Reviews, 2016 - ACS Publications
Push–pull alkenes, which bear electron-donating and-accepting group (s) at both termini of
a C C double bond, respectively, are of interest not only for their unique electronic …

A high affinity red fluorescence and colorimetric probe for amyloid β aggregates

K Rajasekhar, N Narayanaswamy, NA Murugan… - Scientific reports, 2016 - nature.com
A major challenge in the Alzheimer's disease (AD) is its timely diagnosis. Amyloid β (Aβ)
aggregates have been proposed as the most viable biomarker for the diagnosis of AD. Here …