Insulin resistance in polycystic ovary syndrome across various tissues: an updated review of pathogenesis, evaluation, and treatment

H Zhao, J Zhang, X Cheng, X Nie, B He - Journal of Ovarian Research, 2023 - Springer
Polycystic ovary syndrome (PCOS) is a common endocrine disorder characterized by
chronic ovulation dysfunction and overabundance of androgens; it affects 6–20% of women …

Deconstructing a syndrome: genomic insights into PCOS causal mechanisms and classification

M Dapas, A Dunaif - Endocrine reviews, 2022 - academic.oup.com
Polycystic ovary syndrome (PCOS) is among the most common disorders in women of
reproductive age, affecting up to 15% worldwide, depending on the diagnostic criteria …

Insulin resistance and the polycystic ovary syndrome revisited: an update on mechanisms and implications

E Diamanti-Kandarakis, A Dunaif - Endocrine reviews, 2012 - academic.oup.com
Polycystic ovary syndrome (PCOS) is now recognized as an important metabolic as well as
reproductive disorder conferring substantially increased risk for type 2 diabetes. Affected …

Mendelian randomization studies: a review of the approaches used and the quality of reporting

AGC Boef, OM Dekkers… - International journal of …, 2015 - academic.oup.com
Background: Mendelian randomization (MR) studies investigate the effect of genetic
variation in levels of an exposure on an outcome, thereby using genetic variation as an …

Functional genomics of PCOS: from GWAS to molecular mechanisms

JM McAllister, RS Legro, BP Modi, JF Strauss - Trends in Endocrinology & …, 2015 - cell.com
Polycystic ovary syndrome (PCOS) is a common endocrinopathy characterized by increased
ovarian androgen biosynthesis, anovulation, and infertility. PCOS has a strong heritable …

Genetics of the polycystic ovary syndrome

G Kosova, M Urbanek - Molecular and cellular endocrinology, 2013 - Elsevier
Polycystic ovary syndrome (PCOS) is a highly complex endocrine disorder, characterized by
hyperandrogenemia, menstrual irregularities and polycystic ovaries. A strong genetic …

Systematic review: association of polycystic ovary syndrome with metabolic syndrome and non‐alcoholic fatty liver disease

A Baranova, TP Tran, A Birerdinc… - Alimentary …, 2011 - Wiley Online Library
Aliment Pharmacol Ther 2011; 33: 801–814 Summary Background Polycystic ovary
syndrome (PCOS) is a common disorder for women of child‐bearing age and is associated …

Polycystic ovarian syndrome: a complex disease with a genetics approach

H Nautiyal, SS Imam, S Alshehri, MM Ghoneim, M Afzal… - Biomedicines, 2022 - mdpi.com
Polycystic ovarian syndrome (PCOS) is a complex endocrine disorder affecting females in
their reproductive age. The early diagnosis of PCOS is complicated and complex due to …

Molecular & genetic factors contributing to insulin resistance in polycystic ovary syndrome

S Mukherjee, A Maitra - Indian Journal of Medical Research, 2010 - journals.lww.com
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder of unknown
etiology. Insulin resistance is very common and plays a central pathogenic role in PCOS …

The GAPS Programme at TNG-XXXV. Fundamental properties of transiting exoplanet host stars

K Biazzo, V D'Orazi, S Desidera, D Turrini… - Astronomy & …, 2022 - aanda.org
Context. Exoplanetary properties strongly depend on stellar properties: to know the planet
with accuracy and precision it is necessary to know the star as accurately and precisely as …