Iodine is a micronutrient needed for the production of thyroid hormones, which regulate
metabolism, growth, and development. Iodine deficiency or excess may alter the thyroid …

Expression of the sodium iodide symporter (NIS) is required for efficient iodide uptake in
thyroid and lactating breast. Since most differentiated thyroid cancer expresses NIS, β …

The sodium iodide symporter (NIS) is an intrinsic plasma membrane protein that mediates
active iodide transport into the thyroid gland and into several extrathyroidal tissues. NIS …

KLF1 (formerly known as EKLF) regulates the development of erythroid cells from bi-potent
progenitor cells via the transcriptional activation of a diverse set of genes. Mice lacking Klf1 …

The epithelial to mesenchymal transition (EMT) and the mesenchymal to epithelial transition
(MET) are two critical biological processes that are involved in both physiological events …

The Gram-negative bacterial endotoxin lipopolysaccharide (LPS) elicits a variety of
biological responses. Na+/I− symporter (NIS)-mediated iodide uptake is the main rate …

Epithelial–mesenchymal transition (EMT) and mesenchymal–epithelial transition (MET)
highlight crucial steps during embryogenesis and tumorigenesis. Induction of dramatic …

Background Expression and function of sodium iodide symporter (NIS) is requisite for
efficient iodide transport in thyrocytes, and its presence in cancer cells allows the use of …

Introduction The presence, relevance and regulation of the Sodium Iodide Symporter (NIS)
in human mammary tissue remains poorly understood. This study aimed to quantify relative …

Purpose: Retinoic acid (RA) treatment has been used for redifferentiation of metastatic
thyroid cancer with loss of radioiodine uptake. The aim of this study was to improve the …