Model predictive control—a stand out among competitors for fed-batch fermentation improvement

E Bolmanis, K Dubencovs, A Suleiko, J Vanags - Fermentation, 2023 - mdpi.com
The fed-batch cultivation is in many ways a benchmark for fermentation processes, and it
has been an attractive choice for the biotechnological production of various products in the …

[图书][B] Batch fermentation: modeling: monitoring, and control

A Cinar, SJ Parulekar, C Undey, G Birol - 2003 - taylorfrancis.com
Illustrating techniques in model development, signal processing, data reconciliation, process
monitoring, quality assurance, intelligent real-time process supervision, and fault detection …

Artificial neural networks in tandem with molecular descriptors as predictive tools for continuous liposome manufacturing

S Sansare, T Duran, H Mohammadiarani… - International Journal of …, 2021 - Elsevier
The current study utilized an artificial neural network (ANN) to generate computational
models to achieve process optimization for a previously developed continuous liposome …

Optimal control of a fed-batch bioreactor using simulation-based approximate dynamic programming

CV Peroni, NS Kaisare, JH Lee - IEEE Transactions on Control …, 2005 - ieeexplore.ieee.org
In this brief, we extend the simulation-based approximate dynamic programming (ADP)
method to optimal feedback control of fed-batch reactors. We consider a free-end problem …

Dynamic neural networks as a tool for the online optimization of industrial fermentation

T Becker, T Enders, A Delgado - Bioprocess and Biosystems Engineering, 2002 - Springer
A system for online optimization of industrial fermentation based on a model with dynamic
neural networks is described. The developed dynamic neural network, consisting of adapted …

Application of model-predictive control based on artificial neural networks to optimize the fed-batch process for riboflavin production

K Kovárová-Kovar, S Gehlen, A Kunze, T Keller… - Journal of …, 2000 - Elsevier
The fed-batch process for commercial production of riboflavin (vitamin B2) was optimized on-
line using model-predictive control based on artificial neural networks (ANNs). The …

Adaptive optimization of fed-batch culture of yeast by using genetic algorithms

JG Na, YK Chang, BH Chung, HC Lim - Bioprocess and biosystems …, 2002 - Springer
A simulation and experimental study has been carried out on the adaptive optimization of
fed-batch culture of yeast. In the simulation study, three genetic algorithms based on …

Computational intelligence techniques as tools for bioprocess modelling, optimization, supervision and control

MC Nicoletti, LC Jain, RC Giordano - … Intelligence Techniques for …, 2009 - Springer
This is an introductory chapter that presents a general review of some Computational
Intelligence (CI) techniques used today, both in the biotechnology industry and in academic …

Use of neural network models to predict industrial bioreactor effluent quality

GM Pigram, TR MacDonald - Environmental science & technology, 2001 - ACS Publications
Engineered bioreactors are useful tools for degrading wastes from crude oil refining
facilities. One such bioreactor forms part of the wastewater remediation process used at a …

Optimization of operating conditions in rice heat blast process for Chinese rice wine production by combinational utilization of neural network and genetic algorithms

Y Zhu, J Zhang, Z Shi, Z Mao - Journal of the Institute of Brewing, 2004 - Wiley Online Library
The rice heat blast process is a novel technique for gelatinizing raw starch. It uses heated air
to replace steam for processing rice under high temperature fluidization in a short time …