Background Heparin-induced thrombocytopenia (HIT) is an antibody-mediated adverse
drug reaction that can lead to devastating thromboembolic complications, including …

Direct thrombin inhibitors (DTIs) are a new class of anticoagulants that bind directly to
thrombin and block its interaction with its substrates. Four parenteral DTIs have been …

Background: Heparin‐induced thrombocytopenia (HIT) is a prothrombotic adverse drug
reaction caused by heparin. As thrombocytopenia is common in hospitalized patients …

This article about hemorrhagic complications of anticoagulant and thrombolytic treatment is
part of the Antithrombotic and Thrombolytic Therapy: American College of Chest Physicians …

This chapter about the recognition, treatment, and prevention of heparin-induced
thrombocytopenia (HIT) is part of the Antithrombotic and Thrombolytic Therapy: American …

Perioperative bleeding is a major challenge particularly because of increasing clinical use of
potent antithrombotic drugs. Understanding current concepts of coagulation is important in …

Heparin-induced thrombocytopenia (HIT) is a potentially devastating immune mediated
adverse drug reaction caused by the emergence of antibodies that activate platelets in the …

A 63-year-old man with coronary artery disease who has recently undergone bypass
surgery presents with dyspnea. Laboratory testing reveals a platelet count of 86,000 per …

Objectives: To address the issues of Prevention and Management of Acute Renal Failure in
the ICU Patient, using the format of an International Consensus Conference. Methods and …

Immune mediated heparin induced thrombocytopenia (HIT) is a prothrombotic adverse effect
of heparin. However, only a subgroup of patients with HIT develops thromboembolic …