Neurological diseases continue to increase in prevalence worldwide. Combined with the
lack of modifiable risk factors or strongly efficacious therapies, these disorders pose a …

Neurodegenerative diseases (NDs) represent a heterogeneous group of aging-related
disorders featured by progressive impairment of motor and/or cognitive functions, often …

Intranasal drug delivery is as a noninvasive and efficient approach extensively utilized for
treating the local, central nervous system, and systemic diseases. Despite numerous …

Central nervous system disorders significantly affect the lives and health of millions of
people worldwide. Despite many therapeutic drugs are available that could potentially target …

Nanotechnology has proved its tremendous worth in the field of drug delivery and targeting.
Nano formulations have improved the safety and efficacy of various conventional drugs …

Glioblastoma Multiforme (GBM) is a multifaceted and complex disease, which has
experienced no changes in treatment for nearly two decades and has a 5-year survival rate …

We developed a pH-triggered in situ gel (ISG) for ocular delivery of vinpocetine to achieve
systemic absorption and a brain-targeting effect in rats. Carbopol acted as a gelling agent …

Significance: Diabetes is a major source of neuropathy and neuropathic pain that is set to
continue growing in prevalence. Diabetic peripheral neuropathy (DPN) and pain associated …

Objective (s): Migraine, a serious neurological disease that affects millions of people
worldwide, is one of the most considerable burdens on the healthcare system and has …

Improving the apparent solubility of poorly soluble therapeutic molecules with poor
absorption into the circulatory system is a significant research question in drug discovery …