SARS-CoV-2 is the virus responsible for the COVID-19 pandemic. COVID-19 has highly variable disease severity and a bimodal course characterized by acute respiratory viral …
Immune and inflammatory responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) contribute to disease severity of coronavirus disease 2019 (COVID-19) …
Pathologic immune hyperactivation is emerging as a key feature of critical illness in COVID- 19, but the mechanisms involved remain poorly understood. We carried out proteomic …
COVID-19 has claimed millions of lives during the last 3 years since initial cases were reported in Wuhan, China, in 2019. Patients with COVID-19 suffer from severe pneumonia …
Background A systematic review and meta-analysis was performed to estimate mortality in adult patients with solid or hematological malignancies and SARS-CoV-2 infection. Methods …
H Link - Supportive Care in Cancer, 2022 - Springer
Granulocyte colony-stimulating factor (G-CSF), a protein that stimulates the growth of new blood cells, was isolated from human cells by Malcolm Moore and Karl Welte in 1984 [1]. It …
Background The COVID-19 pandemic has created enormous challenges for the clinical management of patients with hematological malignancies (HMs), raising questions about …
KA Mouchemore, RL Anderson - Seminars in immunology, 2021 - Elsevier
Numerous preclinical studies have reported a pro-tumour role for granulocyte colony- stimulating factor (G-CSF) that is predominantly mediated by neutrophils and MDSCs, the …
Despite two years of intense global research activity, host genetic factors that predispose to a poorer prognosis of COVID-19 infection remain poorly understood. Here, we prioritise …