Liver fibrosis is a substantial risk factor for the development and progression of liver cancer,
which includes hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma …

According to the WHO's recently released worldwide cancer data for 2020, liver cancer
ranks sixth in morbidity and third in mortality among all malignancies. Hepatocellular …

Dissecting and understanding the cancer ecosystem, especially that around the tumor
margins, which have strong implications for tumor cell infiltration and invasion, are essential …

Background & Aims Metastasis remains the major reason for the high mortality of patients
with hepatocellular carcinoma (HCC). This study was designed to investigate the role of E …

Background & Aims Remodeling the tumor microenvironment is a critical strategy for treating
advanced hepatocellular carcinoma (HCC). Yet, how distinct cell populations in the …

Hepatocellular carcinoma (HCC) is a common malignancy often associated with high
angiogenesis and immune suppression in the tumor microenvironment (TME). Targeting of …

Liver cancer, primarily hepatocellular carcinoma (HCC), exhibits highly heterogeneous
histological and molecular aberrations across tumors and within individual tumor nodules …

Abstract In Asia–Pacific region, hepatocellular carcinoma is a serious health threat
attributing to over 600,000 deaths each year and account for over 70% of global cases …

Microplastics (MPs) have been detected in various human tissues. However, whether MPs
can accumulate within tumors and how they affect the tumor immune microenvironment …

Non-alcoholic steatohepatitis (NASH) is emerging as a major cause of hepatocellular
carcinoma (HCC), however, it is not resolved if compounds in late-stage clinical …