With the discovery of endothelial progenitor cells (EPCs) in the late 1990s, a paradigm shift
in the concept of neoangiogenesis occurred. The identification of circulating EPCs in …

Stem cell biology has become an important field in regenerative medicine and tissue
engineering therapy since the discovery and characterization of mesenchymal stem cells …

Bioengineered soft tissues on any meaningful scale or complexity must incorporate aspects
of the functional tissue, namely a vasculature, providing cells oxygen and nutrients critical for …

Dentin–pulp complex is a term which refers to the dental pulp (DP) surrounded by dentin
along its peripheries. Dentin and dental pulp are highly specialized tissues, which can be …

Securing an adequate blood supply for the survival of cell transplants is critical for a
successful outcome in tissue engineering. Interactions between endothelial and …

Cellular strategies play an important role in bone tissue engineering and regenerative
medicine (BTE/RM). Variability in cell culture procedures (eg, cell types, cell isolation and …

Recent advances in biomaterial science and tissue engineering technology have greatly
spurred the development of regenerative endodontics. This has led to a paradigm shift in …

Dental caries is a common disease that not only destroys the rigid structure of the teeth but
also causes pulp necrosis in severe cases. Once pulp necrosis has occurred, the most …

The pulp is a highly vascularized tissue situated in an inextensible environment surrounded
by rigid dentin walls, with the apical foramina being the only access. The pulp vascular …

Rapid angiogenesis is one of the challenges in endodontic regeneration. Recently, tailored
polymeric microsphere system that loaded pro-angiogenic growth factors (GFs) is promising …