Macrocycles occupy a unique segment of chemical space. In the past decade, their chemical diversity expanded significantly, supported by advances in bioinformatics and synthetic …
Bioinspired polymeric materials are attracting increasing attention due to significant advantages over their natural counterparts: the ability to precisely tune their structures over a …
I Avan, CD Hall, AR Katritzky - Chemical Society Reviews, 2014 - pubs.rsc.org
Peptidomimetics represent an important field in chemistry, pharmacology and material science as they circumvent the limitations of traditional peptides used in therapy. Self …
In most general terms, polymers and their supramolecular assemblies have been defining life on this planet since its conception. Polymers of nucleic acids carry the code of life and …
Peptoid oligomers were initially developed as part of a larger basic research effort to accelerate the drug‐discovery process in the biotech/biopharma industry. Their ease of …
G Koopmanschap, E Ruijter… - Beilstein Journal of …, 2014 - beilstein-journals.org
In the recent past, the design and synthesis of peptide mimics (peptidomimetics) has received much attention. This because they have shown in many cases enhanced …
EJ Robertson, A Battigelli, C Proulx… - Accounts of Chemical …, 2016 - ACS Publications
Conspectus Two-dimensional (2D) atomically defined organic nanomaterials are an important material class with broad applications. However, few general synthetic methods …
Synthetic macrocycles derived from sequence-defined oligomers are a unique structural class whose ring size, sequence and structure can be tuned via precise organization of the …
Despite their enormous diversity in biological function and structure, peptides and proteins are endowed with properties that have induced and stimulated the development of …