Acanthamoeba keratitis continues to be a difficult infection to diagnose and manage. The
frequency of these infections may be on the rise, most commonly associated with frequent …

Topical drug administration is the preferred route of drug delivery to the eye despite the poor
bioavailability. To develop more efficient drug carriers, reliable in vitro or ex vivo models are …

Epithelia of the cornea, lens and retina contain a vast array of ion channels and pumps.
Together they produce a polarized flow of ions in and out of cells, as well as across the …

Background Metronidazole with well-soluble silver nitrate forms a complex with potent
activity (synergism) against bacterial strains and fungi with simultaneous lower side effect …

Metronidazole eye drops have been used to treat Acanthamoeba keratitis. However,
ophthalmic preparations also have some limitations, one of which is the rapid elimination of …

v13a144-matsumoto pgmkr Page 1 Molecular Vision 2007; 13:1319-26 <http://www.molvis.org/molvis/v13/a144/>
Received 1 May 2007 | Accepted 12 July 2007 | Published 25 July 2007 Although …

Balamuthia mandrillaris is a free living amoeba that can be isolated from soil. It is an
emerging pathogen causing skin lesions as well as CNS involvement with a fatal outcome if …

Concepts and Models for Drug Permeability Studies: Cell and Tissue Based in Vitro Culture
Models, Second Edition, summarizes the most important developments in in vitro models for …

The use of silver preparations in medicine is becoming increasingly popular. The basic aim
of this evaluation was to review the literature on the clinical (in vivo) and antibacterial …

The eye is an intricate organ with multiple defense mechanisms and protective barriers. This
organ is susceptible to infections, hereditary abnormalities, and vision impairments …