Pesticide exposure and the microbiota-gut-brain axis

R Matsuzaki, E Gunnigle, V Geissen, G Clarke… - The ISME …, 2023 - academic.oup.com
The gut microbiota exist within a dynamic ecosystem shaped by various factors that includes
exposure to xenobiotics such as pesticides. It is widely regarded that the gut microbiota …

Impact of glyphosate (RoundupTM) on the composition and functionality of the gut microbiome

L Walsh, C Hill, RP Ross - Gut microbes, 2023 - Taylor & Francis
Glyphosate, the active ingredient in the broad-spectrum herbicide RoundupTM, has been a
topic of discussion for decades due to contradictory reports of the effect of glyphosate on …

Adverse health effects of emerging contaminants on inflammatory bowel disease

X Chen, S Wang, X Mao, X Xiang, S Ye… - Frontiers in Public …, 2023 - frontiersin.org
Inflammatory bowel disease (IBD) is becoming increasingly prevalent with the improvement
of people's living standards in recent years, especially in urban areas. The emerging …

Pesticides and their impairing effects on epithelial barrier integrity, dysbiosis, disruption of the AhR signaling pathway and development of immune-mediated …

C Lima, MAP Falcão, JGS Rosa, GR Disner… - International Journal of …, 2022 - mdpi.com
The environmental and occupational risk we confront from agricultural chemicals increases
as their presence in natural habitats rises to hazardous levels, building a major part of the …

[HTML][HTML] Impact of pesticides exposure during neurodevelopmental period on autism spectrum disorders–A focus on gut microbiota

Y Yang, S Zhou, Y Xing, G Yang, M You - Ecotoxicology and environmental …, 2023 - Elsevier
Accumulating evidence indicates exposure to pesticides during the crucial
neurodevelopmental period increases susceptibility to many diseases, including the …

Effects of glyphosate exposure on intestinal microbiota, metabolism and microstructure: a systematic review

A da Cunha Ignácio, AM dos Reis Guerra… - Food & Function, 2024 - pubs.rsc.org
Glyphosate is the most commercialized herbicide in Brazil and worldwide, and this has
become a worrying scenario in recent years. In 2015 glyphosate was classified as …

[HTML][HTML] Dual-Hit: Glyphosate exposure at NOAEL level negatively impacts birth and glia-behavioural measures in heterozygous shank3 mutants

S Sakkaki, N Cresto, R Chancel, M Jaulmes… - Environment …, 2023 - Elsevier
The omnipresence of environmental contaminants represents a health danger with
ramifications for adverse neurological trajectories. Here, we tested the dual-hit hypothesis …

Development of WaveFlex Biosensor for Rapid Detection of Glyphosate Herbicide in Real Agricultural Products

Q Zhang, C Gu, R Singh, B Zhang… - IEEE Sensors …, 2024 - ieeexplore.ieee.org
Glyphosate is widely used in agriculture and forestry as herbicide. However, excessive use
may lead to water pollution and food safety hazards, which are extremely harmful to …

The herbicide glyphosate inhibits hippocampal long-term potentiation and learning through activation of pro-inflammatory signaling

Y Izumi, KA O'Dell, CF Zorumski - Scientific reports, 2023 - nature.com
Glyphosate, a herbicide marketed as Roundup, is widely used but there are concerns this
exposure could impair cognitive function. In the CA1 region of rat hippocampal slices, we …

A New Family of Macrocyclic Polyamino Biphenolic Ligands: Acid-Base Study, Zn (II) Coordination and Glyphosate/AMPA Binding

GE Giacomazzo, D Paderni, L Giorgi, M Formica… - Molecules, 2023 - mdpi.com
In this study, the ligands 23, 24-dihydroxy-3, 6, 9, 12-tetraazatricyclo [17.3. 1.1 (14, 18)]
eicosatetra-1 (23), 14, 16, 18 (24), 19, 21-hexaene, L1, and 26, 27-dihidroxy-3, 6, 9, 12, 15 …