Targeting bacterial transferrin and lactoferrin receptors for vaccines

AB Schryvers - Trends in microbiology, 2022 - cell.com
A substantial disease burden in vertebrates is due to Gram-negative bacteria that
exclusively inhabit the upper respiratory or genitourinary tracts of their hosts and rely on …

Surveillance on swine farms using antemortem specimens

B Munguía-Ramírez, B Armenta-Leyva… - 2023 - library.oapen.org
In the recent past, disease control on swine farms was based on vaccination or intentional
exposure to pathogens to stimulate immunity and protect against clinical disease. This one …

Hybrid antigens expressing surface loops of BauA from Acinetobacter baumannii are capable of inducing protection against infection

S Chaudhuri, I Rasooli, RH Oskouei… - Frontiers in …, 2022 - frontiersin.org
Acinetobacter baumannii is a human bacterial pathogen of increasing concern in clinical
settings due to the emergence of antibiotic resistant strains and the lack of effective …

[HTML][HTML] Phylogenetic study and comparison of different TbpB obtained from Glaesserella parasuis present in Spanish clinical isolates

AG Fernández, CBG Martín, MP Rilo… - Research in Veterinary …, 2023 - Elsevier
Glaesserella parasuis (Gp) is the etiological agent of Glässer's disease (GD), which causes
important economic losses for the pig intensive production worldwide. This organism uses a …

Molecular characterization of Glaesserella parasuis strains isolated from North America, Europe and Asia by serotyping PCR and LS-PCR

N Macedo, M Gottschalk, K Strutzberg-Minder… - Veterinary …, 2021 - Springer
Glaesserella parasuis strains were characterized by serotyping PCR, vtaA virulence marker
Leader Sequence (LS)-PCR, clinical significance, and geographic region. Overall, the …

Insights from targeting transferrin receptors to develop vaccines for pathogens of humans and food production animals

NF Ewasechko, S Chaudhuri… - Frontiers in Cellular and …, 2023 - frontiersin.org
While developing vaccines targeting surface transferrin receptor proteins in Gram-negative
pathogens of humans and food production animals, the common features derived from their …

TbpB-based oral mucosal vaccine provides heterologous protection against Glässer's disease caused by different serovars of Spanish field isolates of Glaesserella …

A González-Fernández, O Mencía-Ares… - Porcine Health …, 2024 - Springer
Background Glaesserella parasuis (G. parasuis) is the primary agent of Glässer's disease,
significantly affecting nursery and early fattening piglets. Current prophylactic measures …

[HTML][HTML] TbpBY167A-based vaccine can protect pigs against glässer's disease triggered by glaesserella parasuis SV7 expressing TbpB cluster I

SR Prigol, R Klein, S Chaudhuri, GP Frandoloso… - Pathogens, 2022 - ncbi.nlm.nih.gov
Glaesserella parasuis is the etiological agent of Glässer's disease (GD), one of the most
important diseases afflicting pigs in the nursery phase. We analyzed the genetic and …

TbpBY167A-based vaccine is safe in pregnant sows and induces high titers of maternal derived antibodies that reduce Glaesserella parasuis colonization in piglets

D Dellagostin, RL Klein, I Giacobbo, JA Guizzo… - Veterinary …, 2023 - Elsevier
Glässer's disease is one of the main diseases affecting young piglets, particularly during the
nursery phase, that can significantly impact pork production. Vaccination of sows has the …

TbpBY167A-Based Vaccine Can Protect Pigs against Glässer's Disease Triggered by Glaesserella parasuis SV7 Expressing TbpB Cluster I

S Ramos Prigol, R Klein, S Chaudhuri… - Pathogens, 2022 - mdpi.com
Glaesserella parasuis is the etiological agent of Glässer's disease (GD), one of the most
important diseases afflicting pigs in the nursery phase. We analyzed the genetic and …