Delirium and dementia are two frequent causes of cognitive impairment among older adults
and have a distinct, complex and interconnected relationship. Delirium is an acute …

Aging involves the systemic deterioration of all known cell types in most eukaryotes. Several
recently discovered compounds that extend the healthspan and lifespan of model organisms …

The polyamines putrescine, spermidine, and spermine are abundant polycations of vital
importance in mammalian cells. Their cellular levels are tightly regulated by degradation …

Alzheimer's disease (AD) is one of the foremost neurodegenerative diseases, characterized
by beta-amyloid (Aβ) plaques and significant progressive memory loss. In AD, astrocytes are …

Alzheimer's disease (AD) is a neurodegenerative disease characterized by progressive
cognitive impairment and neuroinflammation. Recent research has revealed the crucial role …

The global loss of heterochromatin during ageing has been observed in eukaryotes from
yeast to humans, and this has been proposed as one of the causes of ageing. However, the …

In recent years, extreme environmental cues such as abiotic stresses, including frequent
droughts with irregular precipitation, salinity, metal contamination, and temperature …

Alzheimer's disease (AD) is often comorbid with other pathologies. First, we review shortly
the diseases most associated with AD in the clinic. Then we query PubMed citations for the …

In mammalian cells, the content of polyamines is tightly regulated. Polyamines, including
spermine, spermidine and putrescine, are involved in many cellular processes. Spermine …

Autoimmune diseases (AIDs) are often co-associated, and about 25% of patients with one
AID tend to develop other comorbid AIDs. Here, we employ the power of datamining to …