Astrocytes as guardians of neuronal excitability: mechanisms underlying epileptogenesis

QP Verhoog, L Holtman, E Aronica… - Frontiers in …, 2020 - frontiersin.org
Astrocytes are key homeostatic regulators in the central nervous system and play important
roles in physiology. After brain damage caused by eg, status epilepticus, traumatic brain …

Management of status epilepticus, refractory status epilepticus, and super-refractory status epilepticus

E Trinka, M Leitinger - CONTINUUM: Lifelong Learning in …, 2022 - journals.lww.com
PURPOSE OF REVIEW Status epilepticus is a serious condition caused by disorders and
diseases that affect the central nervous system. In status epilepticus, hypersynchronous …

International consensus recommendations for management of new onset refractory status epilepticus including febrile infection‐related epilepsy syndrome …

R Wickstrom, O Taraschenko, R Dilena, ET Payne… - …, 2022 - Wiley Online Library
Objective This study was undertaken to develop consensus‐based recommendations for the
management of adult and pediatric patients with new onset refractory status epilepticus …

Unraveling the enigma of new‐onset refractory status epilepticus: a systematic review of aetiologies

S Lattanzi, M Leitinger, C Rocchi… - European Journal of …, 2022 - Wiley Online Library
Background and purpose New‐onset refractory status epilepticus (NORSE) is a clinical
presentation, neither a specific diagnosis nor a clinical entity. It refers to a patient without …

New‐onset refractory status epilepticus and febrile infection‐related epilepsy syndrome

N Specchio, N Pietrafusa - Developmental Medicine & Child …, 2020 - Wiley Online Library
New‐onset refractory status epilepticus (NORSE) and febrile infection‐related epilepsy
syndrome (FIRES) are relatively rare clinical presentations. They are characterized by de …

Targeting inflammatory mediators in epilepsy: a systematic review of its molecular basis and clinical applications

G Costagliola, G Depietri, A Michev, A Riva… - Frontiers in …, 2022 - frontiersin.org
Introduction Recent studies prompted the identification of neuroinflammation as a potential
target for the treatment of epilepsy, particularly drug-resistant epilepsy, and refractory status …

A practical approach to in-hospital management of new-onset refractory status epilepticus/febrile infection related epilepsy syndrome

Z Sheikh, LJ Hirsch - Frontiers in Neurology, 2023 - frontiersin.org
New-onset refractory status epilepticus (NORSE) is “a clinical presentation, not a specific
diagnosis, in a patient without active epilepsy or other preexisting relevant neurological …

Towards a treatment for neuroinflammation in epilepsy: interleukin-1 receptor antagonist, anakinra, as a potential treatment in intractable epilepsy

G Yamanaka, Y Ishida, K Kanou, S Suzuki… - International Journal of …, 2021 - mdpi.com
Febrile Infection-Related Epilepsy Syndrome (FIRES) is a unique catastrophic epilepsy
syndrome, and the development of drug-resistant epilepsy (DRE) is inevitable. Recently …

The role of new medical treatments for the management of developmental and epileptic encephalopathies: Novel concepts and results

C Johannessen Landmark, H Potschka, S Auvin… - …, 2021 - Wiley Online Library
Developmental and epileptic encephalopathies (DEEs) are among the most challenging of
all epilepsies to manage, given the exceedingly frequent and often severe seizure types …

New-onset refractory status epilepticus (NORSE)

LM Ritter, L Nashef - Practical Neurology, 2021 - pn.bmj.com
New-onset refractory status epilepticus and its subcategory febrile infection-related epilepsy
syndrome are rare devastating clinical presentations in those without pre-existing relevant …