Metalloenzymes catalyze a variety of reactions using a limited number of natural amino
acids and metallocofactors. Therefore, the environment beyond the primary coordination …

Transition metal-catalysed carbene-and nitrene transfer to the C1-building blocks carbon
monoxide and isocyanides provides heteroallenes (ie ketenes, isocyanates, ketenimines …

Lactones are cyclic esters with extensive applications in materials science, medicinal
chemistry, and the food and perfume industries. Nature's strategy for the synthesis of many …

An efficient iron-catalyzed sulfur alkylation of sulfenamides with 2, 2, 2-trifluorodiazoethane
is developed. The reaction proceeds smoothly at room temperature in an open flask …

Single-atom catalysts (SACs) have generated excitement for their potential to downsize
metal particles to the atomic limit with engineerable local environments and improved …

In nature and synthetic chemistry, stereoselective [2+ 1] cyclopropanation is the most
prevalent strategy for the synthesis of chiral cyclopropanes, a class of key pharmacophores …

The insertion or transfer of carbene using diazo compounds as a precursor is being used
widely to synthesize/functionalize different classes of organic compounds. Different types of …

Despite a well-developed and growing body of work on the directed evolution of
hemoproteins, the potential of hemoproteins to catalyze non-natural reactions remains …

A general catalytic methodology for the synthesis of pyrazolines from α‐diazo compounds
and conjugated alkenes is reported. The direct hydrogen atom transfer (HAT) process of α …

Cyclopropane rings are an important structural motif frequently found in many natural
products and pharmaceuticals. Commonly, biocatalytic methodologies for the asymmetric …