Pathogenic role of exosomes and microRNAs in HPV‐mediated inflammation and cervical cancer: a review

J Sadri Nahand, M Moghoofei… - … journal of cancer, 2020 - Wiley Online Library
Cervical cancer (CC) is the fourth most common cause of cancer death in women. The most
important risk factor for the development of CC is cervical infection with human papilloma …

Immunology of HPV-mediated cervical cancer: current understanding

B Jee, R Yadav, S Pankaj, SK Shahi - International Reviews of …, 2021 - Taylor & Francis
Human papilloma virus (HPV) has emerged as a primary cause of cervical cancer
worldwide. HPV is a relatively small (55 nm in diameter) and non-enveloped virus …

Different subsets of tumor infiltrating lymphocytes correlate with NPC progression in different ways

YL Zhang, J Li, HY Mo, F Qiu, LM Zheng, CN Qian… - Molecular cancer, 2010 - Springer
Background Increasing amounts of evidence indicate that tumor infiltrating lymphocytes (TIL)
are correlated with the prognosis of cancer patients. This study focuses on the association …

Cervical cancer neoantigen landscape and immune activity is associated with human papillomavirus master regulators

Y Qin, S Ekmekcioglu, MA Forget, L Szekvolgyi… - Frontiers in …, 2017 - frontiersin.org
Human papillomaviruses (HPVs) play a major role in development of cervical cancer, and
HPV oncoproteins are being targeted by immunotherapies. Although these treatments show …

The role of interleukin 10 in human papilloma virus infection and progression to cervical carcinoma

FCB Berti, APL Pereira, GCM Cebinelli… - Cytokine & growth factor …, 2017 - Elsevier
Abstract Although Human Papillomavirus (HPV) exerts a vital influence on cervical
carcinogenesis, other factors influence the development of a squamous intraepithelial lesion …

Regulation of immune responses to HPVinfection and during HPV‐directed immunotherapy

P Bhat, SR Mattarollo, C Gosmann… - Immunological …, 2011 - Wiley Online Library
The recent development of vaccines prophylactic against human papillomavirus (HPV)
infection has the potential to reduce the incidence of cervical cancer globally by up to 70 …

High level of Tregs is a positive prognostic marker in patients with HPV‐positive oral and oropharyngeal squamous cell carcinomas

E Lukesova, J Boucek, E Rotnaglova… - BioMed research …, 2014 - Wiley Online Library
Background. Human papillomaviruses (HPVs) have been proved as one of the etiological
factors of oropharyngeal squamous cell carcinoma (OPSCC). Patients with tumors of viral …

The paradox of IL‑10‑mediated modulation in cervical cancer

YAN Wang, XH Liu, YH Li, O Li - Biomedical Reports, 2013 - spandidos-publications.com
Abstract Interleukin-10 (IL-10) has opposing effects as an anti-inflammatory (potentially
cancer-promoting) and antiangiogenic (potentially cancer-inhibiting) agent. The role of IL-10 …

TGFβ Receptor 1: An Immune Susceptibility Gene in HPV-Associated Cancer

C Levovitz, D Chen, E Ivansson, U Gyllensten… - Cancer research, 2014 - AACR
Only a minority of those exposed to human papillomavirus (HPV) develop HPV-related
cervical and oropharyngeal cancer. Because host immunity affects infection and progression …

Local immunosuppression induced by high viral load of human papillomavirus: characterization of cellular phenotypes producing interleukin‐10 in cervical neoplastic …

TTM Prata, CM Bonin, AMT Ferreira… - …, 2015 - Wiley Online Library
A specific immune response to human papillomavirus (HPV) in the cervical
microenvironment plays a key role in eradicating infection and eliminating mutated cells …