Simple Summary The number of children and adults with cancer that are completely cured is
still increasing thanks to effective anti-cancer therapy, but they may be confronted with the …

The microbiota is composed of commensal bacteria and other microorganisms that live on
the epithelial barriers of the host. The commensal microbiota is important for the health and …

The immune system plays a central role in tissue repair and regeneration. Indeed, the
immune response to tissue injury is crucial in determining the speed and the outcome of the …

Toll-like receptors (TLRs) play crucial roles in the innate immune system by recognizing
pathogen-associated molecular patterns derived from various microbes. TLRs signal …

The immunogenicity of cancer cells is an emerging determinant of anti‐cancer
immunotherapy. Beyond developing immunostimulatory regimens like dendritic cell‐based …

Studies that bridge innate immunity and various diseases are making rapid advances.
Macrophages and dendritic cells play a leading role in innate immunity, using pattern …

The majority of therapeutics target membrane proteins, accessible on the surface of cells, to
alter cellular signaling. Cells use membrane proteins to transduce signals into cells …

Purpose Reactive oxygen species (ROS) are produced in cancer cells as a result of
increased metabolic rate, dysfunction of mitochondria, elevated cell signaling, expression of …

Systems biology provides an opportunity to discover the role that gut microbiota play in
almost all aspects of human health. Existing evidence supports the hypothesis that gut …

The respiratory epithelium is the major interface between the environment and the host.
Sophisticated barrier, sensing, anti-microbial and immune regulatory mechanisms have …