Cell shape matters across the kingdoms of life, and cells have the remarkable capacity to
define and maintain specific shapes and sizes. But how are the shapes of micron-sized cells …

It is remarkable how robustly a bacterial species can maintain its preferred size. This
capacity is intimately related to control of the cell cycle: cell size and growth rate determine …

The cellular morphology and sub-cellular spatial structure critically influence the function of
microbial cells. Similarly, the spatial arrangement of genotypes and phenotypes in microbial …

To examine how bacteria achieve robust cell proliferation across diverse conditions, we
developed a method that quantifies 77 cell morphological, cell cycle, and growth …

The scaling of organelles with cell size is thought to be exclusive to eukaryotes. Here, we
demonstrate that similar scaling relationships hold for the bacterial nucleoid. Despite the …

Pioneering work carried out over 60 years ago discovered that bacterial cell size is
proportional to the growth rate set by nutrient availability. This relationship is traditionally …

To win the battle against resistant, pathogenic bacteria, novel classes of anti-infectives and
targets are urgently needed. Bacterial uptake, distribution, metabolic and efflux pathways of …

ABSTRACT CRISPR interference (CRISPRi) has facilitated the study of essential genes in
diverse organisms using both high-throughput and targeted approaches. Despite the …

All viable bacterial cells, whether they divide symmetrically or asymmetrically, must
coordinate their growth, division, cell volume and shape with the inheritance of the genome …

Biological collections are a critical part of the nation's science and innovation infrastructure
and a fundamental resource for understanding the natural world. Biological collections …