Pathophysiological aspects and therapeutic armamentarium of Alzheimer's disease: recent trends and future development

BP Dave, YB Shah, KG Maheshwari… - Cellular and Molecular …, 2023 - Springer
Alzheimer's disease (AD) is the primary cause of dementia and is characterized by the death
of brain cells due to the accumulation of insoluble amyloid plaques, hyperphosphorylation of …

Nanomedicine: A Promising way to manage Alzheimer's disease

NH Khan, M Mir, EE Ngowi, U Zafar… - … in Bioengineering and …, 2021 - frontiersin.org
Alzheimer's disease (AD) is a devastating disease of the aging population characterized by
the progressive and slow brain decay due to the formation of extracellular plaques in the …

Advances on therapeutic strategies for Alzheimer's disease: from medicinal plant to nanotechnology

NA Hassan, AK Alshamari, AA Hassan, MG Elharrif… - Molecules, 2022 - mdpi.com
Alzheimer's disease (AD) is a chronic dysfunction of neurons in the brain leading to
dementia. It is characterized by gradual mental failure, abnormal cognitive functioning …

Spectroscopic, calorimetric and molecular docking insight into the interaction of Alzheimer's drug donepezil with human transferrin: Implications of Alzheimer's drug

A Shamsi, M Al Shahwan, S Ahamad… - Journal of …, 2020 - Taylor & Francis
Donepezil, a highly selective and reversible inhibitor, is amongst the widely used drugs for
the treatment of Alzheimer's disease (AD) across the globe. Clinically significant human …

Role of oxidative stress and metal toxicity in the progression of Alzheimer's disease

H Birla, T Minocha, G Kumar, A Misra… - Current …, 2020 - ingentaconnect.com
Alzheimer's disease (AD) is one of the life-threatening neurodegenerative disorders in the
elderly (> 60 years) and incurable across the globe to date. AD is caused by the involvement …

Developments in treatment methodologies using dendrimers for infectious diseases

N Filipczak, SSK Yalamarty, X Li, F Parveen… - Molecules, 2021 - mdpi.com
Dendrimers comprise a specific group of macromolecules, which combine structural
properties of both single molecules and long expanded polymers. The three-dimensional …

[HTML][HTML] Dendrimers in Alzheimer's disease: recent approaches in multi-targeting strategies

C Arbez-Gindre, BR Steele, M Micha-Screttas - Pharmaceutics, 2023 - mdpi.com
Nanomaterials play an increasingly important role in current medicinal practice. As one of
the most significant causes of human mortality, and one that is increasing year by year …

Future of Alzheimer's disease: nanotechnology-based diagnostics and therapeutic approach

G Agraharam, N Saravanan, A Girigoswami… - BioNanoScience, 2022 - Springer
Alzheimer's disease (AD) is one of the neurodegenerative diseases that leads to the
deposition of amyloid plaques in the neuropil as well as outside the cells in the brain leading …

The application of nanotechnology in treatment of Alzheimer's disease

Y Cao, R Zhang - Frontiers in Bioengineering and Biotechnology, 2022 - frontiersin.org
The buildup of beta-amyloid plaques in the brain results in Alzheimer's disease (AD), a
neurodegenerative condition. A permanent treatment for AD is not yet available. Only a …

[HTML][HTML] Biomaterials-based anti-inflammatory treatment strategies for Alzheimer's disease

J Chu, W Zhang, Y Liu, B Gong, W Ji, T Yin… - Neural Regeneration …, 2024 - journals.lww.com
The current therapeutic drugs for Alzheimer's disease only improve symptoms, they do not
delay disease progression. Therefore, there is an urgent need for new effective drugs. The …