Coriander (Coriandrum sativum): A promising functional food toward the well-being

V Prachayasittikul, S Prachayasittikul… - Food Research …, 2018 - Elsevier
Coriandrum sativum (C. sativum) or coriander is one of the most popularly used spices in
culinary worldwide, and its medicinal values has been recognized since ancient time. C …

[HTML][HTML] Contribution of Nrf2 modulation to the mechanism of action of analgesic and anti-inflammatory drugs in pre-clinical and clinical stages

L Staurengo-Ferrari, S Badaro-Garcia… - Frontiers in …, 2019 - frontiersin.org
Despite the progress that has occurred in recent years in the development of therapies to
treat painful and inflammatory diseases, there is still a need for effective and potent …

Pharmacologic overview of chlorogenic acid and its metabolites in chronic pain and inflammation

D Bagdas, Z Gul, JA Meade, B Cam… - Current …, 2020 - ingentaconnect.com
Background: Natural phenolic compounds in medicinal herbs and dietary plants are
antioxidants which play therapeutic or preventive roles in different pathological situations …

[HTML][HTML] Caffeic acid, a dietary polyphenol, as a promising candidate for combination therapy

S Maity, M Kinra, M Nampoothiri, D Arora, KSR Pai… - Chemical Papers, 2022 - Springer
Increased effectiveness and decreasing toxicity are prime objectives in drug research.
Overwhelming evidence suggests the use of appropriate combination therapy for the better …

[HTML][HTML] Investigation of anti-nociceptive, anti-inflammatory potential and ADMET studies of pure compounds isolated from Isodon rugosus Wall. ex Benth

OM Alshehri, A Zeb, SM Mukarram Shah… - Frontiers in …, 2024 - frontiersin.org
The strong ethnopharmacological utilization of Isodon rugosus Wall. Ex. Benth is evident in
the treatment of several types of pain and inflammation, including toothache, earache …

Does diet play a role in reducing nociception related to inflammation and chronic pain?

G Bjørklund, J Aaseth, MD Doşa, L Pivina, M Dadar… - Nutrition, 2019 - Elsevier
Dietary habits are fundamental issues to assess when modulating health and well-being;
however, different nutritional panels may help individuals prevent acute and chronic pain …

[HTML][HTML] From plant to chemistry: Sources of active opioid antinociceptive principles for medicinal chemistry and drug design

R Turnaturi, S Piana, S Spoto, G Costanzo, L Reina… - Molecules, 2023 - mdpi.com
Pain continues to be an enormous global health challenge, with millions of new untreated or
inadequately treated patients reported annually. With respect to current clinical applications …

Caffeic acid attenuates lipopolysaccharide-induced sickness behaviour and neuroinflammation in mice

SB Mallik, J Mudgal, M Nampoothiri, S Hall… - Neuroscience …, 2016 - Elsevier
Accumulating data links inflammation, oxidative stress and immune system in the
pathophysiology of major depressive disorders. Sickness behaviour is a set of behavioural …

Silymarin liposomes improves oral bioavailability of silybin besides targeting hepatocytes, and immune cells

N Kumar, A Rai, ND Reddy, PV Raj, P Jain… - Pharmacological …, 2014 - Springer
Background: Silymarin, a hepatoprotective agent, has poor oral bioavailability. However, the
current dosage form of the drug does not target the liver and inflammatory cells selectively …

IRAK1/4‐targeted anti‐inflammatory action of caffeic acid

WS Yang, D Jeong, YS Yi, JG Park… - Mediators of …, 2013 - Wiley Online Library
Caffeic acid (CA) is a phenolic compound that is frequently present in fruits, grains, and
dietary supplements. Although CA has been reported to display various biological activities …