Reactive oxygen and nitrogen species (RONS) are generated through various endogenous
and exogenous processes; however, they are neutralized by enzymatic and non-enzymatic …

Acute and chronic lung injuries are among the leading causes of mortality worldwide. Lung
injury can affect several components of the respiratory system, including the airways …

For a long time, superoxide generation by an NADPH oxidase was considered as an oddity
only found in professional phagocytes. Over the last years, six homologs of the cytochrome …

Reactive oxygen species (ROS) serve as cell signaling molecules for normal biologic
processes. However, the generation of ROS can also provoke damage to multiple cellular …

NADPH oxidase (Nox) has a dedicated function of generating reactive oxygen species
(ROS). Accumulating evidence suggests that Nox has an important role in signal …

Oxidative modifications of enzymes and structural proteins play a significant role in the
aetiology and/or progression of several human diseases. Protein carbonyl content is the …

Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in the Western
world. Its incidence has been increasing lately in developing countries. Several lines of …

Increased production of reactive oxygen species (ROS) has been implicated in the
pathogenesis of cardiovascular diseases. Enzymatic systems such as the mitochondrial …

In clinical settings, oxygen therapy is administered to preterm neonates and to adults with
acute and chronic conditions such as COVID-19, pulmonary fibrosis, sepsis, cardiac arrest …

Abundant evidence leaves no doubt that reactive oxygen species (ROS) are not only
inevitable by-products of oxygen metabolism but also play a role in cellular signaling. ROS …