Marine natural products

JW Blunt, BR Copp, WP Hu, MHG Munro… - Natural product …, 2008 - pubs.rsc.org
Covering: 2006. Previous review: Nat. Prod. Rep., 2007, 24, 31 This review covers the
literature published in 2006 for marine natural products, with 758 citations (534 for the …

Conotoxin gene superfamilies

SD Robinson, RS Norton - Marine drugs, 2014 - mdpi.com
Conotoxins are the peptidic components of the venoms of marine cone snails (genus
Conus). They are remarkably diverse in terms of structure and function. Unique potency and …

Conus venoms-a rich source of peptide-based therapeutics

TS Han, RW Teichert, BM Olivera… - Current pharmaceutical …, 2008 - ingentaconnect.com
Over two decades of research on venom peptides derived from cone snails (“conopeptides
or conotoxins”) has led to several compounds that have reached human clinical trials, most …

Diversity of Conotoxin Gene Superfamilies in the Venomous Snail, Conus victoriae

SD Robinson, H Safavi-Hemami, LD McIntosh… - PloS one, 2014 - journals.plos.org
Animal venoms represent a vast library of bioactive peptides and proteins with proven
potential, not only as research tools but also as drug leads and therapeutics. This is …

Folding of Conotoxins: Formation of the Native Disulfide Bridges During Chemical Synthesis and Biosynthesis of Conus Peptides

G Bulaj, BM Olivera - Antioxidants & redox signaling, 2008 - liebertpub.com
Conopeptides from> 700 species of predatory marine Conus snails provide an impressive
molecular diversity of cysteine-rich peptides. Most of the estimated 50,000–100,000 distinct …

Drugs from slugs—Past, present and future perspectives of ω-conotoxin research

JP Bingham, E Mitsunaga, ZL Bergeron - Chemico-biological interactions, 2010 - Elsevier
Peptides from the venom of carnivorous cone shells have provided six decades of intense
research, which has led to the discovery and development of novel analgesic peptide …

Targeting voltage‐gated calcium channels: developments in peptide and small‐molecule inhibitors for the treatment of neuropathic pain

S Vink, PF Alewood - British journal of pharmacology, 2012 - Wiley Online Library
Chronic pain affects approximately 20% of people worldwide and places a large economic
and social burden on society. Despite the availability of a range of analgesics, this condition …

In the picture: disulfide-poor conopeptides, a class of pharmacologically interesting compounds

EKM Lebbe, J Tytgat - Journal of Venomous Animals and Toxins …, 2016 - SciELO Brasil
During evolution, nature has embraced different strategies for species to survive. One
strategy, applied by predators as diverse as snakes, scorpions, sea anemones and cone …

An environmental effect of nano additive on performance and emission in a biofuel fuelled marine engine

S Karthikeyan, A Prathima, K Sabariswaran - 2015 - nopr.niscpr.res.in
The ever increasing population growth and rapid utilization of petroleum based fossil fuels
have induced several crucial environmental problems, such as air pollution, ozone …

The Venom Repertoire of Conus gloriamaris (Chemnitz, 1777), the Glory of the Sea

SD Robinson, Q Li, A Lu, PK Bandyopadhyay… - Marine drugs, 2017 - mdpi.com
The marine cone snail Conus gloriamaris is an iconic species. For over two centuries, its
shell was one of the most prized and valuable natural history objects in the world. Today …