The ectodysplasin (EDA) pathway, which is active during the development of ectodermal
organs, including teeth, hairs, feathers, and mammary glands, and which is crucial for fine …

Recent advances in understanding the molecular events underlying hypohidrotic
ectodermal dysplasia (HED) caused by mutations of the genes encoding proteins of the …

Oligodontia is defined as the congenital lack of six or more permanent teeth, excluding third
molars. Oligodontia as well as hypodontia (lack of one or more permanent teeth) are highly …

Two influential concepts in tissue patterning are Wolpert's positional information and
Turing's self-organized reaction–diffusion (RD). The latter establishes the patterning of hair …

Hypohidrotic ectodermal dysplasia (HED) is characterized by hypotrichosis (sparseness of
scalp and body hair), hypohidrosis (reduced ability to sweat), and hypodontia (congenital …

Ectodermal dysplasias (ED) are a clinically and genetically heterogeneous group of
hereditary disorders that have in common abnormal development of ectodermal derivatives …

Hypohidrotic ectodermal dysplasia (HED) is a rare disorder characterized by deficient
development of structures derived from the ectoderm including hair, nails, eccrine glands …

Ectodermal dysplasias (ED) are uncommon genetic disorders resulting in abnormalities in
ectodermally derived structures. Many ED-associated genes have been described, of which …

Ectodysplasin A (EDA), a ligand of the TNF family, plays an important role in maintaining the
homeostasis of the ocular surface. EDA is necessary for the development of the meibomian …

Background Mutations in the genes encoding components of the tumour necrosis factor
(TNF)‐α‐like pathway cause hypohidrotic ectodermal dysplasia (HED). It has been …