The biological effects of cannabinoids, the major constituents of the ancient medicinal plant
Cannabis sativa (marijuana) are mediated by two members of the G-protein coupled …

The endocannabinoid system (ECS) is composed of two G protein-coupled receptors
(GPCRs), the cannabinoid CB1 and CB2 receptors, and the two main endogenous lipid …

Neurodegeneration leading to Parkinson's disease (PD) and Alzheimer's disease (AD) has
become a major health burden globally. Current treatments mainly target controlling …

The limited effectiveness of current therapies against Alzheimer's disease (AD) highlights
the need for intensifying research efforts devoted to developing new agents for preventing or …

The lack of an adequate therapy for Alzheimer's Disease (AD) contributes greatly to the
continuous growing amount of papers and reviews, reflecting the important efforts made by …

The endocannabinoid system (ECS) exerts a modulatory effect of important functions such
as neurotransmission, glial activation, oxidative stress, or protein homeostasis …

The medicinal properties of cannabis and cannabinoid‐derivative are entirely investigated
and known. In addition, the identification of psychotropic plant cannabinoids has led to more …

Alzheimer's disease (AD) represents the most common form of dementia, characterized by
amyloid β (Aβ) plaques and neurofibrillary tangles (NFTs). It is characterized by …

Alzheimer's disease (AD) is the most common form of progressive neurodegenerative
disease characterized by cognitive impairment and mental disorders. The actual cause and …

Fingolimod (FTY720) is a known sphingosine-1-phosphate (S1P) receptor agonist. Several
studies have shown the therapeutic efficacy of FTY720 in neurodegenerative disorders …