Plant and animal small RNA communications between cells and organisms
Since the discovery of eukaryotic small RNAs as the main effectors of RNA interference in
the late 1990s, diverse types of endogenous small RNAs have been characterized, most …
the late 1990s, diverse types of endogenous small RNAs have been characterized, most …
Small RNAs–big players in plant-microbe interactions
Eukaryotic small RNAs (sRNAs) are short non-coding regulatory molecules that induce RNA
interference (RNAi). During microbial infection, host RNAi machinery is highly regulated and …
interference (RNAi). During microbial infection, host RNAi machinery is highly regulated and …
RNA-binding proteins contribute to small RNA loading in plant extracellular vesicles
Plants use extracellular vesicles (EVs) to transport small RNAs (sRNAs) into their fungal
pathogens and silence fungal virulence-related genes through a phenomenon called 'cross …
pathogens and silence fungal virulence-related genes through a phenomenon called 'cross …
VAP-A and its binding partner CERT drive biogenesis of RNA-containing extracellular vesicles at ER membrane contact sites
RNA transfer via extracellular vesicles (EVs) influences cell phenotypes; however, lack of
information regarding biogenesis of RNA-containing EVs has limited progress in the field …
information regarding biogenesis of RNA-containing EVs has limited progress in the field …
Small RNAs and extracellular vesicles: New mechanisms of cross-species communication and innovative tools for disease control
Small RNA (sRNA)-mediated RNA interference (RNAi) is a conserved regulatory
mechanism for gene expression throughout the domain Eukarya. Recent studies have …
mechanism for gene expression throughout the domain Eukarya. Recent studies have …
[HTML][HTML] Helminth extracellular vesicles: Interactions with the host immune system
C Drurey, RM Maizels - Molecular Immunology, 2021 - Elsevier
As long-lived parasites, helminths depend upon immunomodulation of their hosts for
survival. The release of excretory-secretory (ES) products, including proteins, lipids and …
survival. The release of excretory-secretory (ES) products, including proteins, lipids and …
[HTML][HTML] The protein and microRNA cargo of extracellular vesicles from parasitic helminths–current status and research priorities
J Sotillo, MW Robinson, MJ Kimber, M Cucher… - International journal for …, 2020 - Elsevier
Helminth parasites have a remarkable ability to persist within their mammalian hosts, which
is largely due to their secretion of molecules with immunomodulatory properties. Although …
is largely due to their secretion of molecules with immunomodulatory properties. Although …
The master role of siRNAs in plant immunity
Gene silencing mediated by small noncoding RNAs (sRNAs) is a fundamental gene
regulation mechanism in eukaryotes that broadly governs cellular processes. It has been …
regulation mechanism in eukaryotes that broadly governs cellular processes. It has been …
Revisiting extracellular RNA release, processing, and function
It is assumed that RNAs enriched in extracellular samples were selected for release by their
parental cells. However, recent descriptions of extracellular RNA (exRNA) biogenesis and …
parental cells. However, recent descriptions of extracellular RNA (exRNA) biogenesis and …
Ancient diversity in host-parasite interaction genes in a model parasitic nematode
L Stevens, I Martínez-Ugalde, E King, M Wagah… - Nature …, 2023 - nature.com
Host-parasite interactions exert strong selection pressures on the genomes of both host and
parasite. These interactions can lead to negative frequency-dependent selection, a form of …
parasite. These interactions can lead to negative frequency-dependent selection, a form of …