Excitation-inhibition imbalance in migraine: from neurotransmitters to brain oscillations
Migraine is among the most common and debilitating neurological disorders typically
affecting people of working age. It is characterised by a unilateral, pulsating headache often …
affecting people of working age. It is characterised by a unilateral, pulsating headache often …
Migraine-a borderland disease to epilepsy: near it but not of it
J Paungarttner, M Quartana, L Patti… - The Journal of …, 2024 - Springer
Background Migraine and epilepsy are two paroxysmal chronic neurological disorders
affecting a high number of individuals and being responsible for a high individual and …
affecting a high number of individuals and being responsible for a high individual and …
Morphological and genetic decoding shows heterogeneous patterns of brain aging in chronic musculoskeletal pain
Chronic musculoskeletal pain (CMP), a prevalent and heterogeneous condition
characterized by persistent pain in various body parts, is a leading cause of disability …
characterized by persistent pain in various body parts, is a leading cause of disability …
[HTML][HTML] Meta-analysis and open-source database for in vivo brain Magnetic Resonance spectroscopy in health and disease
AT Gudmundson, A Koo, A Virovka, AL Amirault… - Analytical …, 2023 - Elsevier
Abstract Proton (1 H) Magnetic Resonance Spectroscopy (MRS) is a non-invasive tool
capable of quantifying brain metabolite concentrations in vivo. Prioritization of …
capable of quantifying brain metabolite concentrations in vivo. Prioritization of …
Increase in ACC GABA+ levels correlate with decrease in migraine frequency, intensity and disability over time
Background An imbalance between inhibitory and excitatory neurometabolites has been
implicated in chronic pain. Prior work identified elevated levels of Gamma-aminobutyric …
implicated in chronic pain. Prior work identified elevated levels of Gamma-aminobutyric …
[HTML][HTML] Cortical GABA levels are reduced in young adult binge drinkers: association with recent alcohol consumption and sex
Binge drinking refers to a pattern of alcohol intake that raises blood alcohol concentration to
or above legal intoxication levels. It is common among young adults and is associated with …
or above legal intoxication levels. It is common among young adults and is associated with …
[HTML][HTML] Magnetic resonance spectroscopy studies in migraine
S Nikolova, TJ Schwedt - Neurobiology of Pain, 2022 - Elsevier
This review summarizes major findings and recent advances in magnetic resonance
spectroscopy (MRS) of migraine. A multi database search of PubMed, EMBASE, and Web of …
spectroscopy (MRS) of migraine. A multi database search of PubMed, EMBASE, and Web of …
Deciphering nociplastic pain: clinical features, risk factors and potential mechanisms
Nociplastic pain is a mechanistic term used to describe pain that arises or is sustained by
altered nociception, despite the absence of tissue damage. Although nociplastic pain has …
altered nociception, despite the absence of tissue damage. Although nociplastic pain has …
Neurometabolite levels and relevance to central sensitization in chronic orofacial pain patients: A magnetic resonance spectroscopy study
M Terumitsu, Y Takado, KI Fukuda, E Kato… - Journal of Pain …, 2022 - Taylor & Francis
Background Refractory chronic pain in the orofacial region involves central sensitization
(CS). However, not all chronic pain patients exhibit CS. An objective assessment of CS may …
(CS). However, not all chronic pain patients exhibit CS. An objective assessment of CS may …
A study on the correlation of the asymmetric regulation between the periaqueductal gray and the bilateral trigeminal nucleus caudalis in migraine male rats
Z Cao, W Yu, L Zhang, J Yang, J Lou, M Xu… - The Journal of Headache …, 2023 - Springer
Background The study was designed to explore the correlation of the asymmetric regulation
between periaqueductal gray (PAG) and bilateral trigeminal nucleus caudalis (TNC) in …
between periaqueductal gray (PAG) and bilateral trigeminal nucleus caudalis (TNC) in …