Cyclin-dependent kinases in breast cancer: expression pattern and therapeutic implications
Presently, breast cancer (BC) is one of the most common malignancies diagnosed and the
leading cause of tumor-related deaths among women worldwide. Cell cycle dysregulation is …
leading cause of tumor-related deaths among women worldwide. Cell cycle dysregulation is …
Targeting cyclin-dependent kinase 1 (CDK1) in cancer: molecular docking and dynamic simulations of potential CDK1 inhibitors
Cell cycle dysregulation is a characteristic hallmark of malignancies, which results in
uncontrolled cell proliferation and eventual tumor formation. Cyclin-dependent kinase 1 …
uncontrolled cell proliferation and eventual tumor formation. Cyclin-dependent kinase 1 …
Recent advances in chemotherapeutic implications of deguelin: a plant-derived retinoid
Deguelin, a plant retinoid has emerged to be a promising therapeutic agent in the treatment
of different cancers. Recent studies demonstrate that deguelin has potential as an …
of different cancers. Recent studies demonstrate that deguelin has potential as an …
In vitro and in silico evaluation of antimicrobial properties of Delphinium cashmerianum L., a medicinal herb growing in Kashmir, India
Ethnopharmacological relevance Microorganisms are developing resistance to synthetic
drugs. As a result, the search for novel antimicrobial compounds has become an urgent …
drugs. As a result, the search for novel antimicrobial compounds has become an urgent …
Proteomics: a groundbreaking development in cancer biology
Proteins are the basic unit of any living organism. Proteins are comprised of a variety of
amino acids that drive the structure, stability, and function of proteins. Proteins are the …
amino acids that drive the structure, stability, and function of proteins. Proteins are the …
Proteomics: application of next-generation proteomics in cancer research
Understanding tumor progression and carcinogenesis requires a detailed study of proteins
that play a significant role in the regulation of pathways and processes. Proteins are the …
that play a significant role in the regulation of pathways and processes. Proteins are the …
Repression of Noxa by Bmi1 contributes to deguelin‐induced apoptosis in non‐small cell lung cancer cells
W Li, X Yu, Z Xia, X Yu, L Xie, X Ma… - Journal of Cellular …, 2018 - Wiley Online Library
Deguelin, a natural rotenoid isolated from several plants, has been reported to exert anti‐
tumour effects in various cancers. However, the molecular mechanism of this regulation …
tumour effects in various cancers. However, the molecular mechanism of this regulation …
Evaluation of the in vitro antimicrobial activities of Delphinium roylei: An insight from molecular docking and MD-simulation studies
WR Mir, BA Bhat, A Almilaibary, SMB Asdaq… - Medicinal …, 2022 - ingentaconnect.com
Ethnopharmacological Relevance: The burden of antimicrobial resistance demands a
continued search for new antimicrobial drugs. The synthetic drugs used clinically have …
continued search for new antimicrobial drugs. The synthetic drugs used clinically have …
[HTML][HTML] Intramyocardial injection of hypoxia-conditioned extracellular vesicles modulates apoptotic signaling in chronically ischemic myocardium
DD Harris, SA Sabe, M Sabra, CM Xu, A Malhotra… - JTCVS open, 2023 - Elsevier
Objective Limited treatments exist for nonoperative chronic coronary artery disease.
Previously, our laboratory has investigated extracellular vesicle (EV) therapy as a potential …
Previously, our laboratory has investigated extracellular vesicle (EV) therapy as a potential …
Immuno-onco-metabolism and Therapeutic Resistance
Cancer is a complex succession of disease progressively associated with uncontrolled
growth and capability of cells eluding the body's natural mechanism of defense and cell …
growth and capability of cells eluding the body's natural mechanism of defense and cell …