Neurofilament proteins as biomarkers to monitor neurological diseases and the efficacy of therapies
Biomarkers of neurodegeneration and neuronal injury have the potential to improve
diagnostic accuracy, disease monitoring, prognosis, and measure treatment efficacy …
diagnostic accuracy, disease monitoring, prognosis, and measure treatment efficacy …
Neurofilament-light, a promising biomarker: analytical, metrological and clinical challenges
Neurofilament-light chain (Nf-L) is a non-specific early-stage biomarker widely studied in the
context of neurodegenerative diseases (NDD) and traumatic brain injuries (TBI), which can …
context of neurodegenerative diseases (NDD) and traumatic brain injuries (TBI), which can …
Association of chronic kidney disease with plasma NfL and other biomarkers of neurodegeneration: the H70 birth cohort study in Gothenburg
Background and Objectives Studies associate chronic kidney disease (CKD) with
neurodegeneration. This study investigated the relationship between kidney function, blood …
neurodegeneration. This study investigated the relationship between kidney function, blood …
A comparative study, prediction and development of chronic kidney disease using machine learning on patients clinical records
Abstract Chronic Kidney Disease (CKD) has become a major problem in modern times, and
it is dubbed the silent assassin due to its delayed signs. To overcome these critical issues …
it is dubbed the silent assassin due to its delayed signs. To overcome these critical issues …
Impact of chronic kidney disease on brain structure and function
EJ Steinbach, LA Harshman - Frontiers in neurology, 2022 - frontiersin.org
Chronic kidney disease (CKD) affects more than 37 million American adults. Adult-onset
CKD is typically attributed to acquired comorbidities such as aging, type II diabetes, and …
CKD is typically attributed to acquired comorbidities such as aging, type II diabetes, and …
Quantitative susceptibility mapping and blood neurofilament light chain differentiate between parkinsonian disorders
P Zhang, J Chen, T Cai, C He, Y Li, X Li… - Frontiers in Aging …, 2022 - frontiersin.org
Objectives We employed quantitative susceptibility mapping (QSM) to assess iron
deposition in parkinsonian disorders and explored whether combining QSM values and …
deposition in parkinsonian disorders and explored whether combining QSM values and …
Neurofilament Light Chain as a Biomarker of Global Cognition in Individuals With Possible Vascular Mild Cognitive Impairment
Background Neurofilament Light Chain (NfL) is a biomarker of axonal injury elevated in mild
cognitive impairment (MCI) and Alzheimer's disease dementia. Blood NfL also inversely …
cognitive impairment (MCI) and Alzheimer's disease dementia. Blood NfL also inversely …
Neurofilament light chain: serum reference intervals in Danish children aged 0-17 years
ME Schjørring, T Parkner, CS Knudsen… - … Journal of Clinical …, 2023 - Taylor & Francis
Elevated levels of neurofilament light chain (NfL) in the blood is an unspecific biomarker for
damage to neuronal axons. The measurement of NfL levels in the blood can provide useful …
damage to neuronal axons. The measurement of NfL levels in the blood can provide useful …
Serum Neurofilament light chain (NfL) levels in children with and without neurologic diseases
T Geis, S Gutzeit, S Fouzas, A Ambrosch… - European Journal of …, 2023 - Elsevier
Background/objective Serum neurofilament light chain (sNfL) is a specific biomarker of
neuronal damage. Elevated sNfL levels have been reported in numerous neurologic …
neuronal damage. Elevated sNfL levels have been reported in numerous neurologic …
Neurocognitive deficits may not resolve following pediatric kidney transplantation
Background Pediatric chronic kidney disease (CKD) patients are at risk for cognitive deficits
with worsening disease progression. Limited, existing cross‐sectional studies suggest that …
with worsening disease progression. Limited, existing cross‐sectional studies suggest that …