The development of π-conjugated polymers has provided a gateway to a variety of new
functional organic materials reminiscent of inorganic semiconductors. Nanoparticles based …

After three decades of developments, single particle tracking (SPT) has become a powerful
tool to interrogate dynamics in a range of materials including live cells and novel catalytic …

The slow maturation time of fluorescent proteins (FPs) limits the temporal accuracy of
measurements of rapid processes such as gene expression dynamics and effectively …

Regulation of mRNA translation, the process by which ribosomes decode mRNAs into
polypeptides, is used to tune cellular protein levels. Currently, methods for observing the …

The spatial regulation of protein translation is an efficient way to create functional and
structural asymmetries in cells. Recent research has furthered our understanding of how …

We review the use of luminescent nanoparticles in super-resolution imaging and single-
molecule tracking, and showcase novel approaches to super-resolution imaging that …

Life is characterized by a myriad of complex dynamic processes allowing organisms to grow,
reproduce, and evolve. Physical approaches for describing systems out of thermodynamic …

Understanding how complex phenotypes arise from individual molecules and their
interactions is a primary challenge in biology that computational approaches are poised to …

Although messenger RNA (mRNA) translation is a fundamental biological process, it has
never been imaged in real time in vivo with single-molecule precision. To achieve this, we …

Translation is under tight spatial and temporal controls to ensure protein production in the
right time and place in cells. Methods that allow real-time, high-resolution visualization of …