Diagnosing COVID-19: the disease and tools for detection

B Udugama, P Kadhiresan, HN Kozlowski… - ACS …, 2020 - ACS Publications
COVID-19 has spread globally since its discovery in Hubei province, China in December
2019. A combination of computed tomography imaging, whole genome sequencing, and …

Multifunctional gold nanoparticles for improved diagnostic and therapeutic applications: a review

NRS Sibuyi, KL Moabelo, AO Fadaka, S Meyer… - Nanoscale Research …, 2021 - Springer
The medical properties of metals have been explored for centuries in traditional medicine for
the treatment of infections and diseases and still practiced to date. Platinum-based drugs are …

Bioconjugates of photon-upconversion nanoparticles for cancer biomarker detection and imaging

A Hlaváček, Z Farka, MJ Mickert, U Kostiv… - Nature …, 2022 - nature.com
The detection of cancer biomarkers in histological samples and blood is of paramount
importance for clinical diagnosis. Current methods are limited in terms of sensitivity …

Nanoparticle probes for the detection of cancer biomarkers, cells, and tissues by fluorescence

AB Chinen, CM Guan, JR Ferrer, SN Barnaby… - Chemical …, 2015 - ACS Publications
Cancer is the second most common cause of death in the United States, trailing only heart
disease in incidence. Despite significant worldwide investment in research, cancer remains …

Cancer biomarker detection: recent achievements and challenges

L Wu, X Qu - Chemical Society Reviews, 2015 - pubs.rsc.org
The early detection of cancer can significantly reduce cancer mortality and saves lives. Thus,
a great deal of effort has been devoted to the exploration of new technologies to detect early …

Gold nanoparticles for in vitro diagnostics

W Zhou, X Gao, D Liu, X Chen - Chemical reviews, 2015 - ACS Publications
IVD test is a crucial component of clinical care that performs a diagnostic test on biological
samples that have been taken from a living body, such as blood, urine, and tissue.(1) Such …

Gold nanoparticles in chemical and biological sensing

K Saha, SS Agasti, C Kim, X Li, VM Rotello - Chemical reviews, 2012 - ACS Publications
1. INTRODUCTION Detection of chemical and biological agents plays a fundamental role in
biomedical, forensic and environmental sciences 1− 4 as well as in anti bioterrorism …

Challenges and solutions in developing ultrasensitive biosensors

Y Wu, RD Tilley, JJ Gooding - Journal of the American Chemical …, 2018 - ACS Publications
This Perspective focuses on the latest strategies and challenges for the development of
bioanalytical sensors with sub-picomolar detection limits. Achieving sub-picomolar detection …

Gold nanoparticles: preparation, properties, and applications in bionanotechnology

YC Yeh, B Creran, VM Rotello - Nanoscale, 2012 - pubs.rsc.org
Gold nanoparticles (AuNPs) are important components for biomedical applications. AuNPs
have been widely employed for diagnostics, and have seen increasing use in the area of …

The Simoa HD-1 analyzer: a novel fully automated digital immunoassay analyzer with single-molecule sensitivity and multiplexing

DH Wilson, DM Rissin, CW Kan… - Journal of …, 2016 - journals.sagepub.com
Disease detection at the molecular level is driving the emerging revolution of early diagnosis
and treatment. A challenge facing the field is that protein biomarkers for early diagnosis can …