Obesity is an independent risk factor for severe COVID-19, yet there remains a lack of
consensus on the mechanisms underlying this relationship. A hypothesis that has garnered …

Obesity is associated with impaired immune function, characterized by inflammation, and
leading to poor response to infection, impaired vaccine response, increased susceptibility to …

Suboptimal responses to a primary vaccination course have been reported in the elderly, but
there is little information regarding the impact of age on responses to booster third doses …

Monoclonal antibodies are increasingly used to prevent and treat viral infections and are
pivotal in pandemic response efforts. Antibody-secreting cells (ASCs; plasma cells and …

Background UK COVID-19 vaccination policy has evolved to offering COVID-19 booster
doses to individuals at increased risk of severe Illness from COVID-19. Building on our …

The titer of anti‐severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2)
neutralizing antibodies (NAbs) in the human body is an essential reference for evaluating …

Obesity is a recognized factor influencing immune function and infectious disease outcomes.
Characterization of the influence of obesity on SARS-CoV-2 humoral vaccine …

Objective Class III obesity (body mass index [BMI]≥ 40 kg m− 2) significantly impairs the
immune response to SARS‐CoV‐2 vaccination. However, the effect of an elevated BMI (≥ …

Post-COVID-19 condition is recognized as a multifactorial disorder, with persistent presence
of viral antigens, discordant immunity, delayed viral clearance, and chronic inflammation …

Introduction Current vaccines vary widely in both their efficacy against infection and disease,
and the durability of the efficacy. Some vaccines provide practically lifelong protection with a …