The tremendous biomedical potential of bacterial extracellular vesicles

J Xie, Q Li, F Haesebrouck, L Van Hoecke… - Trends in …, 2022 - cell.com
Bacterial extracellular vesicles (bEVs) are nano-sized, lipid membrane-delimited particles
filled with bacteria-derived components. They have important roles in the physiology and …

Engineered bacterial membrane vesicles are promising carriers for vaccine design and tumor immunotherapy

Q Long, P Zheng, X Zheng, W Li, L Hua, Z Yang… - Advanced drug delivery …, 2022 - Elsevier
Bacterial membrane vesicles (BMVs) have emerged as novel and promising platforms for
the development of vaccines and immunotherapeutic strategies against infectious and …

[HTML][HTML] Engineered bacterial extracellular vesicles for osteoporosis therapy

H Liu, M Li, T Zhang, X Liu, H Zhang, Z Geng… - Chemical Engineering …, 2022 - Elsevier
Osteoporosis (OP) is a systemic bone disease characterized by reduction of bone mass and
destruction of structure, which can easily lead to fragility fractures. Over the past decade, an …

Membrane vesicle production as a bacterial defense against stress

N Mozaheb, MP Mingeot-Leclercq - Frontiers in microbiology, 2020 - frontiersin.org
Membrane vesicles are the nano-sized vesicles originating from membranes. The
production of membrane vesicles is a common feature among bacteria. Depending on the …

Bacterial extracellular vesicles: An emerging postbiotic

J Xie, Q Li, S Nie - Trends in Food Science & Technology, 2024 - Elsevier
Background Our growing appreciation of the functional significance of the human microbiota
in health and disease has triggered a marked interest in bacterial-derived extracellular …

[HTML][HTML] Bacteria and bacterial derivatives as delivery carriers for immunotherapy

SR Kang, DH Nguyen, SW Yoo, JJ Min - Advanced Drug Delivery Reviews, 2022 - Elsevier
There is growing interest in the role of microorganisms in human health and disease, with
evidence showing that new types of biotherapy using engineered bacterial therapeutics …

Bacterial membrane vesicle functions, laboratory methods, and applications

PA Çelik, B Derkuş, K Erdoğan, D Barut… - Biotechnology …, 2022 - Elsevier
Bacterial membrane vesicles (BMVs) are cupped-shaped structures formed by bacteria in
response to environmental stress, genetic alteration, antibiotic exposure, and others. Due to …

[HTML][HTML] Bacterial extracellular vesicle applications in cancer immunotherapy

K Suri, A D'Souza, D Huang, A Bhavsar, M Amiji - Bioactive Materials, 2023 - Elsevier
Cancer therapy is undergoing a paradigm shift toward immunotherapy focusing on various
approaches to activate the host immune system. As research to identify appropriate immune …

Gene transfer potential of outer membrane vesicles of gram-negative bacteria

F Dell'Annunziata, V Folliero, R Giugliano… - International journal of …, 2021 - mdpi.com
The increasing spread of multidrug-resistant pathogenic bacteria is one of the major threats
to public health worldwide. Bacteria can acquire antibiotic resistance and virulence genes …

[HTML][HTML] Bacterial outer membrane vesicle-based cancer nanovaccines

X Gao, Q Feng, J Wang, X Zhao - Cancer Biology & Medicine, 2022 - ncbi.nlm.nih.gov
Tumor vaccines, a type of personalized tumor immunotherapy, have developed rapidly in
recent decades. These vaccines evoke tumor antigen-specific T cells to achieve immune …