Indiscriminate drug administration may lead to drug therapy results with varying effects on
patients, and the proposal of personalized medication can help patients to receive effective …

Alzheimer's disease (AD) is a neurodegenerative disease with significant socioeconomic
burden worldwide. Although genetics and environmental factors play a role, AD is highly …

Abstract Background Trimethylamine N-oxide (TMAO), a gut microbe–generated metabolite,
elicits thrombotic events by enhancing platelet reactivity; however, no studies have reported …

Background: Ticagrelor is an oral antiplatelet agent commonly used to inhibit P2Y12
receptors that bind to it inversely. It is classified as cyclopentyltriazolopyrimidine (CPTP) …

Cardiometabolic diseases (CMDs) are the most common, noncommunicable diseases that
claim many lives every year. CMDs have great impact on public health, often driving the …

Background Coronary artery disease (CAD) claims lives yearly. Nuclear magnetic
resonance (1 H NMR) metabolomics analysis is efficient in identifying metabolic biomarkers …

Dual antiplatelet therapy (DAPT) of clopidogrel and aspirin is crucial for coronary artery
disease (CAD) patients undergoing percutaneous coronary intervention (PCI). However …

Coronary artery disease (CAD), the most common cardiovascular disease (CVD),
contributes to significant mortality worldwide. CAD is a multifactorial disease wherein …

Pharmacometabolomics (PMx) studies aim to predict individual differences in treatment
response and in the development of adverse effects associated with specific drug …

Metabonomics, also known as metabolomics, is concerned with the study of metabolite
profiles in humans, animals, plants and other systems in order to assess their health or other …