The disruption of circadian rhythms by environmental conditions can induce alterations in
body homeostasis, from behavior to metabolism. The light: dark cycle is the most reliable …

During the last 5 to 10 years, the microdialysis technique has been used to explore
neurotransmitter release during exercise. Microdialysis can collect virtually any substance …

Background Myocardial ischemia/reperfusion injury represents a clinically critical problem
associated with coronary artery bypass graft surgery (CABG). The degree of oxidative stress …

The physiological effects of pineal melatonin are primarily mediated by melatonin receptors
located in the brain and periphery. Even though there are a number of studies …

Delirium is a serious neuropsychiatric syndrome of acute onset that occurs in approximately
one in five general hospital patients and is associated with serious adverse outcomes that …

Melatonin is involved in the control of intraocular pressure during the night and day
photoperiod. We have investigated the receptor that regulates intraocular pressure in New …

Melatonin levels, metabolic parameters, circadian rhythm activity patterns, and behavior
were observed in rats subjected to a 12-h/12-h light/dark cycle (LD) compared to animals …

For more than 50 years, Parkinson's disease (PD) has been conceptualized as a product of
nigro-striatal dopamine (NSD) system degeneration. In spite of a growing body of evidence …

Abstract Study Objective: Studying inbred strains of mice has proven useful in uncovering
genetic variation in the expression of sleep patterns. However, although genetic influence …

Systemically administered cholinomimetics or cholinesterase inhibitors can depress
behavior in humans and animals, whereas antimuscarinic agents reverse this effect or even …